DEF8 report

I. Expression across cell types

II. Expression across tissues

sc-RNAseq data

Insufficient scRNA-seq data for expression of DEF8 at tissue level.

III. Associated gene sets

GO_1900029Biological processpositive regulation of ruffle assembly
GO_0045780Biological processpositive regulation of bone resorption
GO_0032418Biological processlysosome localization
GO_0046872Molecular functionmetal ion binding

IV. Literature review

[source]
Gene nameDEF8
Protein nameDifferentially expressed in FDCP 8 homolog (DEF-8)
Alternative protein DEF8
Differentially expressed in FDCP 8 homolog
Synonyms
DescriptionFUNCTION: Positively regulates lysosome peripheral distribution and ruffled border formation in osteoclasts. Involved in bone resorption. .

AccessionsENST00000563594.6 [Q6ZN54-5]
H3BRA7
ENST00000567874.5 [Q6ZN54-4]
L8EAV7
ENST00000567999.5
ENST00000564836.1
ENST00000569061.5
ENST00000562986.5
H3BT01
ENST00000562578.5
H3BQ81
ENST00000561959.5
H3BSH6
H3BMT5
H3BTS7
ENST00000563795.1 [Q6ZN54-6]
ENST00000610455.4 [Q6ZN54-2]
H3BMP4
ENST00000268676.11 [Q6ZN54-1]
ENST00000566079.5
H3BQX9
H3BNN0
Q6ZN54
H3BQH5
ENST00000569453.5 [Q6ZN54-5]
ENST00000418391.6 [Q6ZN54-2]
ENST00000617948.4 [Q6ZN54-5]
ENST00000561784.5
ENST00000561741.5
ENST00000567884.5
H3BT87
ENST00000566820.5
ENST00000570182.5 [Q6ZN54-3]