CYP4A22 | OmnibusX

sc-RNAseq data

Insufficient scRNA-seq data for expression of CYP4A22 at tissue level.

Tissue	GTEx Coverage	GTEx Average TPM	GTEx Number of samples	TCGA Coverage	TCGA Average TPM	TCGA Number of samples
liver	100%	11211.38	226 / 226	90%	50.91	365 / 406
kidney	99%	2426.85	88 / 89	39%	4.97	347 / 901
breast	95%	51.39	438 / 459	7%	0.16	81 / 1118
adipose	96%	54.92	1156 / 1204	0%	0	0 / 0
lung	92%	42.15	529 / 578	1%	0.02	12 / 1155
prostate	81%	16.39	198 / 245	0%	0.00	1 / 502
brain	79%	16.53	2077 / 2642	0%	0	0 / 705
blood vessel	75%	15.03	1000 / 1335	0%	0	0 / 0
thymus	72%	12.59	469 / 653	0%	0	0 / 605
esophagus	70%	12.34	1006 / 1445	1%	0.01	1 / 183
muscle	70%	10.82	561 / 803	0%	0	0 / 0
bladder	67%	11.19	14 / 21	1%	0.01	4 / 504
stomach	66%	10.30	236 / 359	0%	0.01	1 / 286
heart	61%	9.87	522 / 861	0%	0	0 / 0
skin	59%	13.90	1067 / 1809	0%	0.00	1 / 472
uterus	37%	4.92	63 / 170	0%	0.00	1 / 459
intestine	35%	5.34	337 / 966	1%	0.18	6 / 527
pancreas	34%	3.81	111 / 328	2%	0.02	3 / 178
adrenal gland	32%	4.01	83 / 258	0%	0	0 / 230
ovary	13%	1.03	23 / 180	10%	0.30	44 / 430
peripheral blood	14%	4.60	129 / 929	0%	0	0 / 0
spleen	5%	13.37	13 / 241	0%	0	0 / 0
abdomen	0%	0	0 / 0	0%	0	0 / 0
bone marrow	0%	0	0 / 0	0%	0	0 / 0
diaphragm	0%	0	0 / 0	0%	0	0 / 0
eye	0%	0	0 / 0	0%	0	0 / 80
gingiva	0%	0	0 / 0	0%	0	0 / 0
lymph node	0%	0	0 / 0	0%	0	0 / 29
nasal cavity	0%	0	0 / 0	0%	0	0 / 0
nasopharynx	0%	0	0 / 0	0%	0	0 / 0
nose	0%	0	0 / 0	0%	0	0 / 0
placenta	0%	0	0 / 0	0%	0	0 / 0
spinal column	0%	0	0 / 0	0%	0	0 / 0
tonsil	0%	0	0 / 0	0%	0	0 / 45
ureter	0%	0	0 / 0	0%	0	0 / 1

GO_0001822	Biological process	kidney development
GO_0043651	Biological process	linoleic acid metabolic process
GO_0019369	Biological process	arachidonic acid metabolic process
GO_0048252	Biological process	lauric acid metabolic process
GO_0002933	Biological process	lipid hydroxylation
GO_0046456	Biological process	icosanoid biosynthetic process
GO_0097267	Biological process	omega-hydroxylase P450 pathway
GO_0043231	Cellular component	intracellular membrane-bounded organelle
GO_0005615	Cellular component	extracellular space
GO_0005789	Cellular component	endoplasmic reticulum membrane
GO_0008391	Molecular function	arachidonic acid monooxygenase activity
GO_0018685	Molecular function	alkane 1-monooxygenase activity
GO_0102033	Molecular function	long-chain fatty acid omega-hydroxylase activity
GO_0140981	Molecular function	medium-chain fatty acid omega-hydroxylase activity
GO_0005506	Molecular function	iron ion binding
GO_0103002	Molecular function	16-hydroxypalmitate dehydrogenase activity
GO_0052869	Molecular function	arachidonic acid omega-hydroxylase activity
GO_0020037	Molecular function	heme binding

Gene name	CYP4A22
Protein name	Cytochrome P450 family 4 subfamily A member 22 (Cytochrome P450, family 4, subfamily A, polypeptide 22) CYP4A22 protein Cytochrome P450 4A22 (CYPIVA22) (Fatty acid omega-hydroxylase) (Lauric acid omega-hydroxylase) (Long-chain fatty acid omega-monooxygenase) (EC 1.14.14.80) Cytochrome P450 family 4 subfamily A member 22
Synonyms	RP1-18D14.1-003
Description	FUNCTION: Catalyzes the omega- and (omega-1)-hydroxylation of various fatty acids such as laurate and palmitate. Shows no activity towards arachidonic acid and prostaglandin A1. Lacks functional activity in the kidney and does not contribute to renal 20-hydroxyeicosatetraenoic acid (20-HETE) biosynthesis. .
Accessions	ENST00000294337.7 ENST00000619754.4 ENST00000371891.8 [Q5TCH4-1] Q5TCH5 A0A087WZX9 A5PL05 A5PKT5 Q5TCH4 ENST00000371890.7 A0A0C4DFN9

CYP4A22 report