CYP2A7 report

I. Expression across cell types

Insufficient scRNA-seq data for expression of CYP2A7 at single-cell level.

II. Expression across tissues

sc-RNAseq data

Insufficient scRNA-seq data for expression of CYP2A7 at tissue level.

III. Associated gene sets

GO_0019373Biological processepoxygenase P450 pathway
GO_0006805Biological processxenobiotic metabolic process
GO_0009804Biological processcoumarin metabolic process
GO_0043231Cellular componentintracellular membrane-bounded organelle
GO_0005737Cellular componentcytoplasm
GO_0005789Cellular componentendoplasmic reticulum membrane
GO_0019825Molecular functionoxygen binding
GO_0005506Molecular functioniron ion binding
GO_0008392Molecular functionarachidonic acid epoxygenase activity
GO_0020037Molecular functionheme binding
GO_0070330Molecular functionaromatase activity
GO_0016712Molecular functionoxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen

IV. Literature review

[source]
Gene nameCYP2A7
Protein nameCytochrome P450 (EC 1.14.14.1)
Cytochrome P450 2A7 (EC 1.14.14.1) (CYPIIA7) (Cytochrome P450 IIA4)
Cytochrome P450 family 2 subfamily A member 7
Synonyms
DescriptionFUNCTION: Cytochromes P450 are a group of heme-thiolate monooxygenases. In liver microsomes, this enzyme is involved in an NADPH-dependent electron transport pathway. It oxidizes a variety of structurally unrelated compounds, including steroids, fatty acids, and xenobiotics.

FUNCTION: Cytochromes P450 are a group of heme-thiolate monooxygenases. .

FUNCTION: Cytochromes P450 are a group of heme-thiolate monooxygenases. .

AccessionsQ17RW7
ENST00000301146.9
P20853
B7ZKR0
F8W816
M0R020
ENST00000291764.3
ENST00000594332.1