CYP2A13 report

I. Expression across cell types

Insufficient scRNA-seq data for expression of CYP2A13 at single-cell level.

II. Expression across tissues

sc-RNAseq data

Insufficient scRNA-seq data for expression of CYP2A13 at tissue level.

III. Associated gene sets

GO_0019373Biological processepoxygenase P450 pathway
GO_0046222Biological processaflatoxin metabolic process
GO_0006805Biological processxenobiotic metabolic process
GO_0009804Biological processcoumarin metabolic process
GO_0043231Cellular componentintracellular membrane-bounded organelle
GO_0005737Cellular componentcytoplasm
GO_0005789Cellular componentendoplasmic reticulum membrane
GO_0008389Molecular functioncoumarin 7-hydroxylase activity
GO_0004497Molecular functionmonooxygenase activity
GO_0005506Molecular functioniron ion binding
GO_0008392Molecular functionarachidonic acid epoxygenase activity
GO_0020037Molecular functionheme binding
GO_0070330Molecular functionaromatase activity
GO_0016712Molecular functionoxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen

IV. Literature review

[source]
Gene nameCYP2A13
Protein nameCytochrome P450 2A13 (EC 1.14.14.1) (CYPIIA13)
Synonyms
DescriptionFUNCTION: Exhibits a coumarin 7-hydroxylase activity. Active in the metabolic activation of hexamethylphosphoramide, N,N-dimethylaniline, 2'-methoxyacetophenone, N-nitrosomethylphenylamine, and the tobacco-specific carcinogen, 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone. Possesses phenacetin O-deethylation activity. .

AccessionsENST00000330436.4
Q16696