I. Expression across cell types
Name | Number of supported studies  | Average coverage | |
|---|---|---|---|
| type I pneumocyte | 7 studies | 25% ± 6% | |
| erythrocyte | 3 studies | 33% ± 9% |
Name | Number of supported studies | Average coverage | |
|---|---|---|---|
| type I pneumocyte | 7 studies | 25% ± 6% | |
| erythrocyte | 3 studies | 33% ± 9% |
Insufficient scRNA-seq data for expression of CTSE at tissue level.
Tissue | GTEx Coverage | GTEx Average TPM | GTEx Number of samples | TCGA Coverage | TCGA Average TPM | TCGA Number of samples |
|---|---|---|---|---|---|---|
| lung | 99% | 3420.41 | 575 / 578 | 69% | 215.35 | 800 / 1155 |
| stomach | 86% | 19272.33 | 309 / 359 | 60% | 272.57 | 171 / 286 |
| pancreas | 57% | 245.42 | 186 / 328 | 87% | 741.27 | 155 / 178 |
| thymus | 97% | 996.13 | 633 / 653 | 46% | 25.64 | 278 / 605 |
| ureter | 0% | 0 | 0 / 0 | 100% | 25.37 | 1 / 1 |
| intestine | 43% | 297.28 | 418 / 966 | 54% | 189.78 | 283 / 527 |
| bladder | 43% | 362.10 | 9 / 21 | 32% | 70.96 | 161 / 504 |
| esophagus | 2% | 26.46 | 28 / 1445 | 39% | 246.76 | 72 / 183 |
| peripheral blood | 37% | 82.78 | 345 / 929 | 0% | 0 | 0 / 0 |
| kidney | 11% | 14.71 | 10 / 89 | 4% | 4.15 | 36 / 901 |
| uterus | 1% | 4.28 | 1 / 170 | 11% | 16.90 | 52 / 459 |
| liver | 3% | 3.73 | 6 / 226 | 7% | 10.40 | 30 / 406 |
| ovary | 1% | 7.68 | 2 / 180 | 4% | 1.92 | 17 / 430 |
| heart | 4% | 11.79 | 34 / 861 | 0% | 0 | 0 / 0 |
| spleen | 3% | 6.36 | 8 / 241 | 0% | 0 | 0 / 0 |
| tonsil | 0% | 0 | 0 / 0 | 2% | 0.75 | 1 / 45 |
| breast | 2% | 6.97 | 7 / 459 | 1% | 0.45 | 7 / 1118 |
| adipose | 2% | 12.91 | 23 / 1204 | 0% | 0 | 0 / 0 |
| blood vessel | 2% | 6.51 | 23 / 1335 | 0% | 0 | 0 / 0 |
| prostate | 1% | 3.14 | 3 / 245 | 0% | 0.07 | 2 / 502 |
| skin | 0% | 0.43 | 6 / 1809 | 1% | 0.51 | 6 / 472 |
| muscle | 0% | 0.31 | 1 / 803 | 0% | 0 | 0 / 0 |
| brain | 0% | 0.16 | 3 / 2642 | 0% | 0 | 0 / 705 |
| abdomen | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| adrenal gland | 0% | 0 | 0 / 258 | 0% | 0 | 0 / 230 |
| bone marrow | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| diaphragm | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| eye | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 80 |
| gingiva | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| lymph node | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 29 |
| nasal cavity | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| nasopharynx | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| nose | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| placenta | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| spinal column | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| GO_0019886 | Biological process | antigen processing and presentation of exogenous peptide antigen via MHC class II |
| GO_0016540 | Biological process | protein autoprocessing |
| GO_0006508 | Biological process | proteolysis |
| GO_0043231 | Cellular component | intracellular membrane-bounded organelle |
| GO_0005768 | Cellular component | endosome |
| GO_0004190 | Molecular function | aspartic-type endopeptidase activity |
| GO_0008233 | Molecular function | peptidase activity |
| GO_0042802 | Molecular function | identical protein binding |
| Gene name | CTSE |
| Protein name | Cathepsin E (EC 3.4.23.34) Cathepsin E Cathepsin E (EC 3.4.23.34) [Cleaved into: Cathepsin E form I; Cathepsin E form II] |
| Synonyms | |
| Description | FUNCTION: May have a role in immune function. Probably involved in the processing of antigenic peptides during MHC class II-mediated antigen presentation. May play a role in activation-induced lymphocyte depletion in the thymus, and in neuronal degeneration and glial cell activation in the brain. . FUNCTION: May have a role in immune function. Probably involved in the processing of antigenic peptides during MHC class II-mediated antigen presentation. May play a role in activation-induced lymphocyte depletion in the thymus, and in neuronal degeneration and glial cell activation in the brain. . FUNCTION: May have a role in immune function. Probably involved in the processing of antigenic peptides during MHC class II-mediated antigen presentation. May play a role in activation-induced lymphocyte depletion in the thymus, and in neuronal degeneration and glial cell activation in the brain. . FUNCTION: May have a role in immune function. Probably involved in the processing of antigenic peptides during MHC class II-mediated antigen presentation. May play a role in activation-induced lymphocyte depletion in the thymus, and in neuronal degeneration and glial cell activation in the brain. . FUNCTION: May have a role in immune function. Probably involved in the processing of antigenic peptides during MHC class II-mediated antigen presentation. May play a role in activation-induced lymphocyte depletion in the thymus, and in neuronal degeneration and glial cell activation in the brain. . |
| Accessions | P14091 A0A7I2V648 A0A7P0MPN9 ENST00000678285.1 ENST00000678498.1 [P14091-2] ENST00000358184.7 [P14091-1] ENST00000360218.3 A0A7I2V4K7 ENST00000677780.1 A0A7I2V480 A0A7I2V4C5 ENST00000678712.1 ENST00000677924.1 |
