Name | Number of supported studies | Average coverage | |
---|---|---|---|
adipocyte | 10 studies | 57% ± 18% | |
astrocyte | 9 studies | 25% ± 10% | |
fibroblast | 7 studies | 21% ± 4% | |
endothelial cell | 7 studies | 32% ± 12% | |
glutamatergic neuron | 7 studies | 41% ± 24% | |
GABAergic neuron | 7 studies | 39% ± 17% | |
oligodendrocyte | 7 studies | 28% ± 10% | |
epithelial cell | 5 studies | 30% ± 11% | |
interneuron | 5 studies | 34% ± 16% | |
oligodendrocyte precursor cell | 4 studies | 34% ± 11% | |
connective tissue cell | 3 studies | 20% ± 2% | |
abnormal cell | 3 studies | 22% ± 6% | |
microglial cell | 3 studies | 22% ± 1% | |
ciliated cell | 3 studies | 18% ± 2% | |
hepatocyte | 3 studies | 38% ± 11% | |
smooth muscle cell | 3 studies | 19% ± 2% | |
pericyte | 3 studies | 19% ± 3% | |
neuron | 3 studies | 31% ± 9% |
Tissue | GTEx Coverage | GTEx Average TPM | GTEx Number of samples | TCGA Coverage | TCGA Average TPM | TCGA Number of samples |
---|---|---|---|---|---|---|
prostate | 100% | 4440.49 | 245 / 245 | 99% | 16.56 | 496 / 502 |
adrenal gland | 100% | 2197.98 | 258 / 258 | 98% | 10.07 | 226 / 230 |
esophagus | 100% | 2542.54 | 1444 / 1445 | 98% | 10.67 | 179 / 183 |
breast | 100% | 5287.61 | 459 / 459 | 97% | 22.15 | 1090 / 1118 |
uterus | 100% | 3507.82 | 170 / 170 | 97% | 14.86 | 446 / 459 |
ovary | 100% | 4057.17 | 180 / 180 | 95% | 14.17 | 410 / 430 |
thymus | 100% | 3235.22 | 652 / 653 | 95% | 13.64 | 576 / 605 |
brain | 97% | 1952.68 | 2571 / 2642 | 97% | 13.93 | 686 / 705 |
liver | 100% | 4256.63 | 226 / 226 | 94% | 14.31 | 380 / 406 |
pancreas | 100% | 1616.39 | 327 / 328 | 93% | 9.68 | 165 / 178 |
bladder | 100% | 2110.71 | 21 / 21 | 91% | 10.72 | 461 / 504 |
lung | 100% | 2488.65 | 577 / 578 | 88% | 10.05 | 1017 / 1155 |
kidney | 100% | 2667.65 | 89 / 89 | 87% | 11.09 | 784 / 901 |
intestine | 100% | 2483.09 | 966 / 966 | 83% | 6.49 | 440 / 527 |
stomach | 100% | 1966.05 | 358 / 359 | 83% | 5.98 | 237 / 286 |
skin | 98% | 2169.47 | 1772 / 1809 | 80% | 7.77 | 377 / 472 |
adipose | 100% | 5568.02 | 1204 / 1204 | 0% | 0 | 0 / 0 |
spleen | 100% | 3077.31 | 241 / 241 | 0% | 0 | 0 / 0 |
ureter | 0% | 0 | 0 / 0 | 100% | 8.20 | 1 / 1 |
blood vessel | 100% | 2809.07 | 1332 / 1335 | 0% | 0 | 0 / 0 |
heart | 93% | 1210.44 | 800 / 861 | 0% | 0 | 0 / 0 |
peripheral blood | 93% | 1433.70 | 862 / 929 | 0% | 0 | 0 / 0 |
tonsil | 0% | 0 | 0 / 0 | 89% | 11.86 | 40 / 45 |
lymph node | 0% | 0 | 0 / 0 | 83% | 5.95 | 24 / 29 |
eye | 0% | 0 | 0 / 0 | 78% | 8.67 | 62 / 80 |
muscle | 75% | 656.13 | 602 / 803 | 0% | 0 | 0 / 0 |
abdomen | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
bone marrow | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
diaphragm | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
gingiva | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
nasal cavity | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
nasopharynx | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
nose | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
placenta | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
spinal column | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
GO_0019449 | Biological process | L-cysteine catabolic process to hypotaurine |
GO_0019452 | Biological process | L-cysteine catabolic process to taurine |
GO_0042412 | Biological process | taurine biosynthetic process |
GO_0005737 | Cellular component | cytoplasm |
GO_0004068 | Molecular function | aspartate 1-decarboxylase activity |
GO_0030170 | Molecular function | pyridoxal phosphate binding |
GO_0004782 | Molecular function | sulfinoalanine decarboxylase activity |
Gene name | CSAD |
Protein name | Cysteine sulfinic acid decarboxylase (EC 4.1.1.29) (Aspartate 1-decarboxylase) (EC 4.1.1.11) (Cysteine-sulfinate decarboxylase) (Sulfinoalanine decarboxylase) Cysteine sulfinic acid decarboxylase CSAD protein Cysteine sulfinic acid decarboxylase (Cysteine sulfinic acid decarboxylase-related protein 1) |
Synonyms | hCG_43754 CSD |
Description | FUNCTION: Catalyzes the decarboxylation of L-aspartate, 3-sulfino-L-alanine (cysteine sulfinic acid), and L-cysteate to beta-alanine, hypotaurine and taurine, respectively. The preferred substrate is 3-sulfino-L-alanine. Does not exhibit any decarboxylation activity toward glutamate. . |
Accessions | C9JTU8 F8WCW3 ENST00000437073.5 ENST00000444623.6 [Q9Y600-1] F8VV11 ENST00000548698.5 ENST00000424845.5 H3BTP4 ENST00000498635.1 Q86V02 ENST00000475890.5 ENST00000483632.5 ENST00000379850.7 J3KPG9 H3BQ59 F6XLJ2 ENST00000424990.5 Q9Y600 ENST00000379846.5 [Q9Y600-2] ENST00000267085.8 [Q9Y600-3] ENST00000453446.6 [Q9Y600-1] E9PFW9 |