CRYZ report

I. Expression across cell types

II. Expression across tissues

III. Associated gene sets

GO_0007601Biological processvisual perception
GO_0042178Biological processxenobiotic catabolic process
GO_0051289Biological processprotein homotetramerization
GO_0070062Cellular componentextracellular exosome
GO_0005829Cellular componentcytosol
GO_0003960Molecular functionNADPH:quinone reductase activity
GO_0070402Molecular functionNADPH binding
GO_0003730Molecular functionmRNA 3'-UTR binding
GO_0042802Molecular functionidentical protein binding
GO_0008270Molecular functionzinc ion binding
GO_0070404Molecular functionNADH binding

IV. Literature review

[source]
Gene nameCRYZ
Protein nameQuinone oxidoreductase (EC 1.6.5.5) (NADPH:quinone reductase) (Zeta-crystallin)
Synonyms
DescriptionFUNCTION: Does not have alcohol dehydrogenase activity. Binds NADP and acts through a one-electron transfer process. Orthoquinones, such as 1,2-naphthoquinone or 9,10-phenanthrenequinone, are the best substrates (in vitro). May act in the detoxification of xenobiotics. Interacts with (AU)-rich elements (ARE) in the 3'-UTR of target mRNA species. Enhances the stability of mRNA coding for BCL2. NADPH binding interferes with mRNA binding. .

AccessionsQ08257
ENST00000370870.5
C9JH92
ENST00000340866.10 [Q08257-1]
ENST00000441120.1
ENST00000370872.7 [Q08257-2]
ENST00000370871.7 [Q08257-3]
ENST00000417775.5 [Q08257-1]
A6NP24