COQ8B report

I. Expression across cell types

II. Expression across tissues

III. Associated gene sets

GO_0021692Biological processcerebellar Purkinje cell layer morphogenesis
GO_0006468Biological processprotein phosphorylation
GO_0006744Biological processubiquinone biosynthetic process
GO_0031966Cellular componentmitochondrial membrane
GO_0005829Cellular componentcytosol
GO_0005886Cellular componentplasma membrane
GO_0005739Cellular componentmitochondrion
GO_0004672Molecular functionprotein kinase activity
GO_0008289Molecular functionlipid binding
GO_0016887Molecular functionATP hydrolysis activity
GO_0005524Molecular functionATP binding

IV. Literature review

[source]
Gene nameCOQ8B
Protein nameAtypical kinase COQ8B, mitochondrial
Atypical kinase COQ8B, mitochondrial (EC 2.7.-.-) (AarF domain-containing protein kinase 4) (Coenzyme Q protein 8B)
Coenzyme Q8B
SynonymsADCK4
DescriptionFUNCTION: Atypical kinase involved in the biosynthesis of coenzyme Q, also named ubiquinone, an essential lipid-soluble electron transporter for aerobic cellular respiration . Its substrate specificity is unclear: does not show any protein kinase activity. Probably acts as a small molecule kinase, possibly a lipid kinase that phosphorylates a prenyl lipid in the ubiquinone biosynthesis pathway. Required for podocyte migration . .

AccessionsA0A7I2V559
ENST00000599643.5
M0R0L2
ENST00000677517.1
ENST00000678419.1 [Q96D53-1]
ENST00000678316.1
ENST00000678057.1
M0R2F4
M0R001
A0A7I2V5Z5
M0QZZ2
ENST00000594720
A0A7I2V3G8
ENST00000679130.1 [Q96D53-1]
ENST00000677018.1 [Q96D53-1]
A0A7I2V2R1
ENST00000600080.5
ENST00000677496.1
ENST00000594084.5
A0A7I2V4Z6
ENST00000677633.1
M0R362
ENST00000596357.1
M0R307
ENST00000676555.1
M0R0F4
ENST00000679315.1
ENST00000595254.5
ENST00000594720.6 [Q96D53-1]
M0R3F7
ENST00000601967.6 [Q96D53-1]
ENST00000678467.1 [Q96D53-1]
ENST00000678569.1
A0A7I2V4T3
ENST00000679070.1
M0R011
ENST00000601304.5
ENST00000677800.1
ENST00000676578.1
ENST00000600707.5
ENST00000601967
A0A7I2V3W7
A0A7I2V455
ENST00000243583.10 [Q96D53-2]
ENST00000678404.1 [Q96D53-1]
ENST00000679012.1
ENST00000594490.6
M0R340
A0A7I2V3Y0
ENST00000324464.8 [Q96D53-1]
Q96D53
A0A7I2V544