COPZ2 report

I. Expression across cell types

II. Expression across tissues

sc-RNAseq data

Insufficient scRNA-seq data for expression of COPZ2 at tissue level.

III. Associated gene sets

GO_0006886Biological processintracellular protein transport
GO_0006890Biological processretrograde vesicle-mediated transport, Golgi to endoplasmic reticulum
GO_0006891Biological processintra-Golgi vesicle-mediated transport
GO_0033116Cellular componentendoplasmic reticulum-Golgi intermediate compartment membrane
GO_0000139Cellular componentGolgi membrane
GO_0005801Cellular componentcis-Golgi network
GO_0030126Cellular componentCOPI vesicle coat
GO_0005829Cellular componentcytosol
GO_0005789Cellular componentendoplasmic reticulum membrane
GO_0030133Cellular componenttransport vesicle

IV. Literature review

[source]
Gene nameCOPZ2
Protein nameCoatomer subunit zeta
COPI coat complex subunit zeta 2
Coatomer subunit zeta-2 (Zeta-2-coat protein) (Zeta-2 COP)
Synonyms
DescriptionFUNCTION: The coatomer is a cytosolic protein complex that binds to dilysine motifs and reversibly associates with Golgi non-clathrin-coated vesicles, which further mediate biosynthetic protein transport from the ER, via the Golgi up to the trans Golgi network. Coatomer complex is required for budding from Golgi membranes, and is essential for the retrograde Golgi-to-ER transport of dilysine-tagged proteins. The zeta subunit may be involved in regulating the coat assembly and, hence, the rate of biosynthetic protein transport due to its association-dissociation properties with the coatomer complex. .

FUNCTION: The zeta subunit may be involved in regulating the coat assembly and, hence, the rate of biosynthetic protein transport due to its association-dissociation properties with the coatomer complex. .

FUNCTION: The zeta subunit may be involved in regulating the coat assembly and, hence, the rate of biosynthetic protein transport due to its association-dissociation properties with the coatomer complex. .

FUNCTION: The zeta subunit may be involved in regulating the coat assembly and, hence, the rate of biosynthetic protein transport due to its association-dissociation properties with the coatomer complex. .

FUNCTION: The zeta subunit may be involved in regulating the coat assembly and, hence, the rate of biosynthetic protein transport due to its association-dissociation properties with the coatomer complex. .

AccessionsJ3KRJ9
J3QQQ5
ENST00000580174.1
ENST00000583414.5
ENST00000581637.5
Q9P299
ENST00000621465.5
J3QS21
ENST00000584955.5
J3QL73
A0A0G2JLH9
J3QLS7
ENST00000579263.1
ENST00000581756.5