CNGA2 report

I. Expression across cell types

Insufficient scRNA-seq data for expression of CNGA2 at single-cell level.

II. Expression across tissues

sc-RNAseq data

Insufficient scRNA-seq data for expression of CNGA2 at tissue level.

III. Associated gene sets

GO_0006813Biological processpotassium ion transport
GO_0007608Biological processsensory perception of smell
GO_0006814Biological processsodium ion transport
GO_0098655Biological processmonoatomic cation transmembrane transport
GO_0006816Biological processcalcium ion transport
GO_0070588Biological processcalcium ion transmembrane transport
GO_0060170Cellular componentciliary membrane
GO_0098804Cellular componentnon-motile cilium membrane
GO_0030660Cellular componentGolgi-associated vesicle membrane
GO_0017071Cellular componentintracellular cyclic nucleotide activated cation channel complex
GO_0005886Cellular componentplasma membrane
GO_0044877Molecular functionprotein-containing complex binding
GO_0005222Molecular functionintracellularly cAMP-activated cation channel activity
GO_0005223Molecular functionintracellularly cGMP-activated cation channel activity
GO_0030552Molecular functioncAMP binding
GO_0005516Molecular functioncalmodulin binding
GO_0005262Molecular functioncalcium channel activity
GO_0030553Molecular functioncGMP binding

IV. Literature review

[source]
Gene nameCNGA2
Protein nameCyclic nucleotide-gated olfactory channel (Cyclic nucleotide-gated cation channel 2) (Cyclic nucleotide-gated channel alpha-2) (CNG channel alpha-2) (CNG-2) (CNG2)
SynonymsCNCA
CNCA1
CNCG2
DescriptionFUNCTION: Odorant signal transduction is probably mediated by a G-protein coupled cascade using cAMP as second messenger. The olfactory channel can be shown to be activated by cyclic nucleotides which leads to a depolarization of olfactory sensory neurons.

AccessionsQ16280
ENST00000329903.5