CMYA5 report

I. Expression across cell types

II. Expression across tissues

III. Associated gene sets

GO_0043231Cellular componentintracellular membrane-bounded organelle
GO_0016607Cellular componentnuclear speck
GO_0031430Cellular componentM band
GO_0005829Cellular componentcytosol
GO_0005886Cellular componentplasma membrane
GO_0016529Cellular componentsarcoplasmic reticulum
GO_0048471Cellular componentperinuclear region of cytoplasm
GO_0005737Cellular componentcytoplasm
GO_0005634Cellular componentnucleus

IV. Literature review

[source]
Gene nameCMYA5
Protein nameCardiomyopathy-associated protein 5 (Dystrobrevin-binding protein 2) (Genethonin-3) (Myospryn) (SPRY domain-containing protein 2) (Tripartite motif-containing protein 76)
SynonymsC5orf10
DTNBP2
SPRYD2
TRIM76
DescriptionFUNCTION: May serve as an anchoring protein that mediates the subcellular compartmentation of protein kinase A (PKA) via binding to PRKAR2A (By similarity). May function as a repressor of calcineurin-mediated transcriptional activity. May attenuate calcineurin ability to induce slow-fiber gene program in muscle and may negatively modulate skeletal muscle regeneration (By similarity). Plays a role in the assembly of ryanodine receptor (RYR2) clusters in striated muscle (By similarity). .

AccessionsQ8N3K9
ENST00000446378.3