CMAHP report

I. Expression across cell types

Insufficient scRNA-seq data for expression of CMAHP at single-cell level.

II. Expression across tissues

sc-RNAseq data

Insufficient scRNA-seq data for expression of CMAHP at tissue level.

III. Associated gene sets

GO_0046381Biological processCMP-N-acetylneuraminate metabolic process
GO_0030111Biological processregulation of Wnt signaling pathway
GO_0005856Cellular componentcytoskeleton
GO_0016020Cellular componentmembrane
GO_0005737Cellular componentcytoplasm
GO_0005634Cellular componentnucleus
GO_0030338Molecular functionCMP-N-acetylneuraminate monooxygenase activity

IV. Literature review

[source]
Gene nameCMAHP
Protein nameInactive cytidine monophosphate-N-acetylneuraminic acid hydroxylase (CMP-NeuAc hydroxylase-like protein) (Cytidine monophosphate-N-acetylneuraminic acid hydroxylase pseudogene)
SynonymsCMAH
DescriptionFUNCTION: Sialic acids are components of carbohydrate chains of glycoconjugates and are involved in cell-cell recognition and cell-pathogen interactions. That protein has no CMP-N-acetylneuraminate monooxygenase activity and is not able to convert CMP-N-acetylneuraminic acid (CMP-Neu5Ac) into its hydroxylated derivative CMP-N-glycolylneuraminic acid (CMP-Neu5Gc), a sialic acid abundantly expressed at the surface of many cells in vertebrates . However, it may play a role in Wnt signaling . .

AccessionsQ9Y471