CLEC9A report

I. Expression across cell types

II. Expression across tissues

sc-RNAseq data

Insufficient scRNA-seq data for expression of CLEC9A at tissue level.

III. Associated gene sets

GO_0001819Biological processpositive regulation of cytokine production
GO_0006898Biological processreceptor-mediated endocytosis
GO_0009986Cellular componentcell surface
GO_0016020Cellular componentmembrane
GO_0030246Molecular functioncarbohydrate binding

IV. Literature review

[source]
Gene nameCLEC9A
Protein nameC-type lectin domain family 9 member A (CD antigen CD370)
SynonymsUNQ9341/PRO34046
DescriptionFUNCTION: Functions as an endocytic receptor on a small subset of myeloid cells specialized for the uptake and processing of material from dead cells. Recognizes filamentous form of actin in association with particular actin-binding domains of cytoskeletal proteins, including spectrin, exposed when cell membranes are damaged, and mediate the cross-presentation of dead-cell associated antigens in a Syk-dependent manner. .

AccessionsQ6UXN8
ENST00000355819.6