CLCNKA | OmnibusX

Name	Number of supported studies	Average coverage
kidney loop of Henle epithelial cell	6 studies	28% ± 10%	Explore
renal alpha-intercalated cell	5 studies	46% ± 23%	Explore
ionocyte	4 studies	28% ± 10%	Explore
kidney distal convoluted tubule epithelial cell	4 studies	40% ± 10%	Explore

sc-RNAseq data

Insufficient scRNA-seq data for expression of CLCNKA at tissue level.

Tissue	GTEx Coverage	GTEx Average TPM	GTEx Number of samples	TCGA Coverage	TCGA Average TPM	TCGA Number of samples
thymus	100%	4003.20	653 / 653	44%	4.60	269 / 605
kidney	100%	11052.37	89 / 89	42%	10.97	378 / 901
adrenal gland	96%	466.67	247 / 258	38%	5.77	88 / 230
ovary	85%	145.84	153 / 180	41%	1.25	176 / 430
pancreas	99%	313.23	326 / 328	17%	0.38	31 / 178
prostate	83%	138.66	203 / 245	32%	0.59	159 / 502
uterus	85%	171.87	145 / 170	14%	0.40	64 / 459
stomach	90%	403.62	322 / 359	6%	0.12	18 / 286
breast	66%	153.18	302 / 459	27%	0.59	298 / 1118
eye	0%	0	0 / 0	85%	4.37	68 / 80
skin	40%	83.52	731 / 1809	11%	0.48	52 / 472
blood vessel	51%	62.67	676 / 1335	0%	0	0 / 0
lung	34%	40.84	197 / 578	15%	0.48	175 / 1155
adipose	44%	68.26	532 / 1204	0%	0	0 / 0
esophagus	34%	50.69	494 / 1445	7%	0.20	12 / 183
intestine	31%	36.87	300 / 966	3%	0.09	15 / 527
muscle	33%	43.65	263 / 803	0%	0	0 / 0
liver	8%	9.63	18 / 226	22%	0.75	90 / 406
brain	21%	184.70	560 / 2642	4%	0.06	25 / 705
heart	23%	24.12	202 / 861	0%	0	0 / 0
bladder	10%	8.38	2 / 21	6%	0.26	28 / 504
lymph node	0%	0	0 / 0	14%	0.51	4 / 29
spleen	6%	5.93	14 / 241	0%	0	0 / 0
peripheral blood	4%	4.33	37 / 929	0%	0	0 / 0
abdomen	0%	0	0 / 0	0%	0	0 / 0
bone marrow	0%	0	0 / 0	0%	0	0 / 0
diaphragm	0%	0	0 / 0	0%	0	0 / 0
gingiva	0%	0	0 / 0	0%	0	0 / 0
nasal cavity	0%	0	0 / 0	0%	0	0 / 0
nasopharynx	0%	0	0 / 0	0%	0	0 / 0
nose	0%	0	0 / 0	0%	0	0 / 0
placenta	0%	0	0 / 0	0%	0	0 / 0
spinal column	0%	0	0 / 0	0%	0	0 / 0
tonsil	0%	0	0 / 0	0%	0	0 / 45
ureter	0%	0	0 / 0	0%	0	0 / 1

GO_0070293	Biological process	renal absorption
GO_1902476	Biological process	chloride transmembrane transport
GO_0030321	Biological process	transepithelial chloride transport
GO_0006821	Biological process	chloride transport
GO_0034707	Cellular component	chloride channel complex
GO_0005886	Cellular component	plasma membrane
GO_0042802	Molecular function	identical protein binding
GO_0005247	Molecular function	voltage-gated chloride channel activity
GO_0046872	Molecular function	metal ion binding

Gene name	CLCNKA
Protein name	Chloride channel protein ClC-Ka (Chloride channel Ka) (ClC-K1)
Synonyms
Description	FUNCTION: Voltage-gated chloride channel. Chloride channels have several functions including the regulation of cell volume; membrane potential stabilization, signal transduction and transepithelial transport. May be important in urinary concentrating mechanisms.
Accessions	ENST00000375692.5 [P51800-3] ENST00000439316.6 [P51800-2] ENST00000331433.5 [P51800-1] P51800

CLCNKA report