CHST7 report

I. Expression across cell types

II. Expression across tissues

sc-RNAseq data

Insufficient scRNA-seq data for expression of CHST7 at tissue level.

III. Associated gene sets

GO_0006044Biological processN-acetylglucosamine metabolic process
GO_0030206Biological processchondroitin sulfate biosynthetic process
GO_0005976Biological processpolysaccharide metabolic process
GO_0006790Biological processsulfur compound metabolic process
GO_0005802Cellular componenttrans-Golgi network
GO_0000139Cellular componentGolgi membrane
GO_0016020Cellular componentmembrane
GO_0008459Molecular functionchondroitin 6-sulfotransferase activity
GO_0001517Molecular functionN-acetylglucosamine 6-O-sulfotransferase activity

IV. Literature review

[source]
Gene nameCHST7
Protein nameCarbohydrate sulfotransferase 7 (EC 2.8.2.-) (EC 2.8.2.17) (Chondroitin 6-sulfotransferase 2) (C6ST-2) (Galactose/N-acetylglucosamine/N-acetylglucosamine 6-O-sulfotransferase 5) (GST-5) (N-acetylglucosamine 6-O-sulfotransferase 4) (GlcNAc6ST-4) (Gn6st-4)
Alternative protein CHST7
Synonyms
DescriptionFUNCTION: Sulfotransferase that utilizes 3'-phospho-5'-adenylyl sulfate (PAPS) as sulfonate donor to catalyze the transfer of sulfate to position 6 of non-reducing N-acetylglucosamine (GlcNAc) residues. Preferentially acts on mannose-linked GlcNAc. Also able to catalyze the transfer of sulfate to position 6 of the N-acetylgalactosamine (GalNAc) residue of chondroitin. Also acts on core 2 mucin-type oligosaccharide and N-acetyllactosamine oligomer with a lower efficiency. Has weak or no activity toward keratan sulfate and oligosaccharides containing the Galbeta1-4GlcNAc. Catalyzes 6-O-sulfation of beta-benzyl GlcNAc but not alpha- or beta-benzyl GalNAc. .

AccessionsENST00000276055.4
Q9NS84
L8EA50