Name | Number of supported studies | Average coverage | |
|---|---|---|---|
| myeloid cell | 3 studies | 24% ± 4% |
Insufficient scRNA-seq data for expression of CHIT1 at tissue level.
Tissue | GTEx Coverage | GTEx Average TPM | GTEx Number of samples | TCGA Coverage | TCGA Average TPM | TCGA Number of samples |
|---|---|---|---|---|---|---|
| lung | 96% | 1891.73 | 553 / 578 | 66% | 23.37 | 762 / 1155 |
| thymus | 57% | 170.52 | 374 / 653 | 58% | 14.37 | 349 / 605 |
| spleen | 100% | 739.48 | 240 / 241 | 0% | 0 | 0 / 0 |
| peripheral blood | 99% | 1445.09 | 920 / 929 | 0% | 0 | 0 / 0 |
| breast | 61% | 422.62 | 281 / 459 | 30% | 8.68 | 336 / 1118 |
| adipose | 72% | 961.29 | 865 / 1204 | 0% | 0 | 0 / 0 |
| lymph node | 0% | 0 | 0 / 0 | 69% | 161.30 | 20 / 29 |
| prostate | 21% | 33.58 | 51 / 245 | 40% | 4.93 | 200 / 502 |
| pancreas | 14% | 11.91 | 45 / 328 | 46% | 8.54 | 81 / 178 |
| brain | 38% | 74.31 | 992 / 2642 | 18% | 2.80 | 129 / 705 |
| kidney | 11% | 11.81 | 10 / 89 | 39% | 15.25 | 347 / 901 |
| tonsil | 0% | 0 | 0 / 0 | 49% | 13.82 | 22 / 45 |
| intestine | 26% | 41.28 | 249 / 966 | 18% | 1.91 | 94 / 527 |
| skin | 8% | 21.95 | 147 / 1809 | 28% | 12.39 | 134 / 472 |
| uterus | 9% | 43.25 | 16 / 170 | 25% | 3.68 | 116 / 459 |
| eye | 0% | 0 | 0 / 0 | 34% | 7.25 | 27 / 80 |
| stomach | 9% | 5.63 | 32 / 359 | 20% | 3.52 | 58 / 286 |
| ovary | 17% | 55.56 | 30 / 180 | 8% | 0.86 | 34 / 430 |
| adrenal gland | 21% | 34.70 | 54 / 258 | 3% | 0.25 | 7 / 230 |
| esophagus | 8% | 5.60 | 121 / 1445 | 15% | 3.20 | 28 / 183 |
| liver | 12% | 9.63 | 28 / 226 | 10% | 2.66 | 39 / 406 |
| blood vessel | 21% | 189.28 | 281 / 1335 | 0% | 0 | 0 / 0 |
| muscle | 21% | 30.59 | 169 / 803 | 0% | 0 | 0 / 0 |
| bladder | 0% | 0 | 0 / 21 | 21% | 3.22 | 104 / 504 |
| heart | 8% | 6.69 | 70 / 861 | 0% | 0 | 0 / 0 |
| abdomen | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| bone marrow | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| diaphragm | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| gingiva | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| nasal cavity | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| nasopharynx | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| nose | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| placenta | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| spinal column | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| ureter | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 1 |
| GO_0006955 | Biological process | immune response |
| GO_0000272 | Biological process | polysaccharide catabolic process |
| GO_0006032 | Biological process | chitin catabolic process |
| GO_0044245 | Biological process | polysaccharide digestion |
| GO_0009617 | Biological process | response to bacterium |
| GO_0005615 | Cellular component | extracellular space |
| GO_0005764 | Cellular component | lysosome |
| GO_1904724 | Cellular component | tertiary granule lumen |
| GO_0005576 | Cellular component | extracellular region |
| GO_0035580 | Cellular component | specific granule lumen |
| GO_0008843 | Molecular function | endochitinase activity |
| GO_0004553 | Molecular function | hydrolase activity, hydrolyzing O-glycosyl compounds |
| GO_0004568 | Molecular function | chitinase activity |
| GO_0008061 | Molecular function | chitin binding |
| Gene name | CHIT1 |
| Protein name | Chitinase 1 Chitotriosidase-1 (EC 3.2.1.14) (Chitinase-1) |
| Synonyms | |
| Description | FUNCTION: Degrades chitin, chitotriose and chitobiose. May participate in the defense against nematodes and other pathogens. Isoform 3 has no enzymatic activity. . |
| Accessions | ENST00000491855.5 [Q13231-2] ENST00000255427.7 [Q13231-4] ENST00000503786.1 ENST00000367229.6 [Q13231-1] D6REY1 Q13231 |