CHIT1 report

I. Expression across cell types

II. Expression across tissues

sc-RNAseq data

Insufficient scRNA-seq data for expression of CHIT1 at tissue level.

III. Associated gene sets

GO_0006955Biological processimmune response
GO_0000272Biological processpolysaccharide catabolic process
GO_0006032Biological processchitin catabolic process
GO_0044245Biological processpolysaccharide digestion
GO_0009617Biological processresponse to bacterium
GO_0005615Cellular componentextracellular space
GO_0005764Cellular componentlysosome
GO_1904724Cellular componenttertiary granule lumen
GO_0005576Cellular componentextracellular region
GO_0035580Cellular componentspecific granule lumen
GO_0008843Molecular functionendochitinase activity
GO_0004553Molecular functionhydrolase activity, hydrolyzing O-glycosyl compounds
GO_0004568Molecular functionchitinase activity
GO_0008061Molecular functionchitin binding

IV. Literature review

[source]
Gene nameCHIT1
Protein nameChitinase 1
Chitotriosidase-1 (EC 3.2.1.14) (Chitinase-1)
Synonyms
DescriptionFUNCTION: Degrades chitin, chitotriose and chitobiose. May participate in the defense against nematodes and other pathogens. Isoform 3 has no enzymatic activity. .

AccessionsENST00000491855.5 [Q13231-2]
ENST00000255427.7 [Q13231-4]
ENST00000503786.1
ENST00000367229.6 [Q13231-1]
D6REY1
Q13231