I. Expression across cell types
Name | Number of supported studies  | Average coverage | |
|---|---|---|---|
| endothelial cell | 5 studies | 30% ± 5% |
Name | Number of supported studies | Average coverage | |
|---|---|---|---|
| endothelial cell | 5 studies | 30% ± 5% |
Insufficient scRNA-seq data for expression of CETP at tissue level.
Tissue | GTEx Coverage | GTEx Average TPM | GTEx Number of samples | TCGA Coverage | TCGA Average TPM | TCGA Number of samples |
|---|---|---|---|---|---|---|
| kidney | 100% | 250.56 | 89 / 89 | 94% | 8.58 | 849 / 901 |
| thymus | 100% | 445.66 | 651 / 653 | 88% | 6.34 | 530 / 605 |
| liver | 96% | 329.70 | 218 / 226 | 88% | 4.43 | 356 / 406 |
| adrenal gland | 99% | 158.89 | 256 / 258 | 79% | 3.32 | 181 / 230 |
| lung | 98% | 184.03 | 567 / 578 | 70% | 1.56 | 805 / 1155 |
| breast | 82% | 529.12 | 378 / 459 | 72% | 1.54 | 807 / 1118 |
| brain | 41% | 26.22 | 1087 / 2642 | 83% | 2.89 | 582 / 705 |
| lymph node | 0% | 0 | 0 / 0 | 100% | 29.10 | 29 / 29 |
| spleen | 100% | 2088.52 | 241 / 241 | 0% | 0 | 0 / 0 |
| skin | 25% | 15.67 | 459 / 1809 | 73% | 7.31 | 345 / 472 |
| intestine | 45% | 53.04 | 439 / 966 | 51% | 1.18 | 268 / 527 |
| adipose | 95% | 545.88 | 1149 / 1204 | 0% | 0 | 0 / 0 |
| pancreas | 29% | 14.71 | 95 / 328 | 66% | 1.83 | 117 / 178 |
| uterus | 39% | 23.75 | 67 / 170 | 54% | 1.30 | 247 / 459 |
| bladder | 48% | 26.00 | 10 / 21 | 44% | 1.08 | 221 / 504 |
| stomach | 30% | 18.23 | 106 / 359 | 60% | 1.36 | 171 / 286 |
| peripheral blood | 89% | 159.45 | 828 / 929 | 0% | 0 | 0 / 0 |
| prostate | 53% | 29.52 | 129 / 245 | 31% | 0.58 | 155 / 502 |
| esophagus | 16% | 8.47 | 232 / 1445 | 67% | 1.73 | 122 / 183 |
| eye | 0% | 0 | 0 / 0 | 83% | 4.62 | 66 / 80 |
| tonsil | 0% | 0 | 0 / 0 | 58% | 1.15 | 26 / 45 |
| heart | 41% | 26.85 | 351 / 861 | 0% | 0 | 0 / 0 |
| ovary | 9% | 3.63 | 16 / 180 | 28% | 0.54 | 119 / 430 |
| blood vessel | 34% | 28.31 | 450 / 1335 | 0% | 0 | 0 / 0 |
| muscle | 11% | 6.42 | 90 / 803 | 0% | 0 | 0 / 0 |
| abdomen | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| bone marrow | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| diaphragm | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| gingiva | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| nasal cavity | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| nasopharynx | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| nose | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| placenta | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| spinal column | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| ureter | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 1 |
| GO_0070328 | Biological process | triglyceride homeostasis |
| GO_0055091 | Biological process | phospholipid homeostasis |
| GO_0015914 | Biological process | phospholipid transport |
| GO_0034372 | Biological process | very-low-density lipoprotein particle remodeling |
| GO_0008203 | Biological process | cholesterol metabolic process |
| GO_0043691 | Biological process | reverse cholesterol transport |
| GO_0034197 | Biological process | triglyceride transport |
| GO_0034375 | Biological process | high-density lipoprotein particle remodeling |
| GO_0032376 | Biological process | positive regulation of cholesterol transport |
| GO_0010745 | Biological process | negative regulation of macrophage derived foam cell differentiation |
| GO_0034374 | Biological process | low-density lipoprotein particle remodeling |
| GO_2001140 | Biological process | positive regulation of phospholipid transport |
| GO_0006641 | Biological process | triglyceride metabolic process |
| GO_0046470 | Biological process | phosphatidylcholine metabolic process |
| GO_0010874 | Biological process | regulation of cholesterol efflux |
| GO_0055088 | Biological process | lipid homeostasis |
| GO_0030301 | Biological process | cholesterol transport |
| GO_0006869 | Biological process | lipid transport |
| GO_0042632 | Biological process | cholesterol homeostasis |
| GO_0005615 | Cellular component | extracellular space |
| GO_0005576 | Cellular component | extracellular region |
| GO_0070062 | Cellular component | extracellular exosome |
| GO_0034364 | Cellular component | high-density lipoprotein particle |
| GO_0031982 | Cellular component | vesicle |
| GO_0015485 | Molecular function | cholesterol binding |
| GO_0008289 | Molecular function | lipid binding |
| GO_0120020 | Molecular function | cholesterol transfer activity |
| GO_0031210 | Molecular function | phosphatidylcholine binding |
| GO_0005548 | Molecular function | phospholipid transporter activity |
| GO_0017129 | Molecular function | triglyceride binding |
| Gene name | CETP |
| Protein name | Cholesteryl ester transfer protein Cholesteryl ester transfer protein (Lipid transfer protein I) |
| Synonyms | hCG_23902 |
| Description | FUNCTION: Involved in the transfer of neutral lipids, including cholesteryl ester and triglyceride, among lipoprotein particles. Allows the net movement of cholesteryl ester from high density lipoproteins/HDL to triglyceride-rich very low density lipoproteins/VLDL, and the equimolar transport of triglyceride from VLDL to HDL . Regulates the reverse cholesterol transport, by which excess cholesterol is removed from peripheral tissues and returned to the liver for elimination . . FUNCTION: Involved in the transfer of neutral lipids, including cholesteryl ester and triglyceride, among lipoprotein particles. Allows the net movement of cholesteryl ester from high density lipoproteins/HDL to triglyceride-rich very low density lipoproteins/VLDL, and the equimolar transport of triglyceride from VLDL to HDL. . |
| Accessions | Q9H4L8 Q8IWL9 F4YZX8 ENST00000200676.8 [P11597-1] H3BRJ9 ENST00000566128.1 ENST00000379780.6 [P11597-2] A0A0S2Z3F6 P11597 A0A0S2Z3I8 |
