CENPN report

I. Expression across cell types

II. Expression across tissues

sc-RNAseq data

Insufficient scRNA-seq data for expression of CENPN at tissue level.

III. Associated gene sets

GO_0034080Biological processCENP-A containing chromatin assembly
GO_0007059Biological processchromosome segregation
GO_0005654Cellular componentnucleoplasm
GO_0005829Cellular componentcytosol
GO_0000939Cellular componentinner kinetochore
GO_0005634Cellular componentnucleus

IV. Literature review

[source]
Gene nameCENPN
Protein nameCentromere protein N
Centromere protein N (CENP-N) (Interphase centromere complex protein 32)
SynonymsBM-309
ICEN32
C16orf60
DescriptionFUNCTION: Component of the CENPA-NAC (nucleosome-associated) complex, a complex that plays a central role in assembly of kinetochore proteins, mitotic progression and chromosome segregation. The CENPA-NAC complex recruits the CENPA-CAD (nucleosome distal) complex and may be involved in incorporation of newly synthesized CENPA into centromeres. CENPN is the first protein to bind specifically to CENPA nucleosomes and the direct binding of CENPA nucleosomes by CENPN is required for centromere assembly. Required for chromosome congression and efficiently align the chromosomes on a metaphase plate. .

AccessionsENST00000305850.10 [Q96H22-1]
ENST00000393335.7 [Q96H22-3]
Q96H22
ENST00000439957.7 [Q96H22-4]
ENST00000709374.1 [Q96H22-5]
H3BMC7
H3BRU7
ENST00000428963.6 [Q96H22-5]
H3BMD5
ENST00000709372.1 [Q96H22-3]
ENST00000564669.5
ENST00000709370.1 [Q96H22-2]
ENST00000568445.1
ENST00000562943.1
ENST00000709369.1 [Q96H22-1]
ENST00000299572.9 [Q96H22-2]
ENST00000709371.1 [Q96H22-4]