Name | Number of supported studies | Average coverage | |
---|---|---|---|
epithelial cell | 3 studies | 26% ± 6% | |
erythroblast | 3 studies | 33% ± 21% | |
erythrocyte | 3 studies | 26% ± 14% | |
CD8-positive, alpha-beta T cell | 3 studies | 19% ± 5% |
Insufficient scRNA-seq data for expression of CENPN at tissue level.
Tissue | GTEx Coverage | GTEx Average TPM | GTEx Number of samples | TCGA Coverage | TCGA Average TPM | TCGA Number of samples |
---|---|---|---|---|---|---|
esophagus | 99% | 228.12 | 1434 / 1445 | 100% | 14.78 | 183 / 183 |
stomach | 99% | 184.53 | 357 / 359 | 100% | 11.04 | 285 / 286 |
prostate | 100% | 1352.95 | 245 / 245 | 99% | 35.97 | 497 / 502 |
skin | 99% | 516.99 | 1795 / 1809 | 98% | 12.75 | 463 / 472 |
intestine | 100% | 181.66 | 962 / 966 | 98% | 10.87 | 515 / 527 |
lung | 99% | 220.77 | 573 / 578 | 97% | 9.91 | 1122 / 1155 |
bladder | 100% | 158.86 | 21 / 21 | 96% | 10.16 | 483 / 504 |
uterus | 95% | 85.40 | 162 / 170 | 98% | 13.38 | 451 / 459 |
breast | 100% | 147.51 | 458 / 459 | 93% | 7.11 | 1037 / 1118 |
ovary | 94% | 84.78 | 169 / 180 | 96% | 6.42 | 411 / 430 |
pancreas | 94% | 90.57 | 307 / 328 | 92% | 4.73 | 163 / 178 |
liver | 100% | 188.66 | 226 / 226 | 82% | 4.38 | 334 / 406 |
brain | 98% | 145.52 | 2594 / 2642 | 84% | 4.99 | 589 / 705 |
kidney | 100% | 153.56 | 89 / 89 | 66% | 2.63 | 599 / 901 |
adrenal gland | 100% | 256.02 | 258 / 258 | 60% | 3.25 | 139 / 230 |
thymus | 99% | 139.43 | 648 / 653 | 60% | 2.61 | 365 / 605 |
lymph node | 0% | 0 | 0 / 0 | 100% | 11.90 | 29 / 29 |
spleen | 100% | 241.60 | 241 / 241 | 0% | 0 | 0 / 0 |
tonsil | 0% | 0 | 0 / 0 | 100% | 15.58 | 45 / 45 |
ureter | 0% | 0 | 0 / 0 | 100% | 5.14 | 1 / 1 |
adipose | 100% | 177.73 | 1203 / 1204 | 0% | 0 | 0 / 0 |
blood vessel | 99% | 136.18 | 1317 / 1335 | 0% | 0 | 0 / 0 |
muscle | 98% | 153.85 | 787 / 803 | 0% | 0 | 0 / 0 |
heart | 94% | 204.56 | 810 / 861 | 0% | 0 | 0 / 0 |
eye | 0% | 0 | 0 / 0 | 78% | 3.40 | 62 / 80 |
peripheral blood | 69% | 387.39 | 641 / 929 | 0% | 0 | 0 / 0 |
abdomen | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
bone marrow | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
diaphragm | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
gingiva | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
nasal cavity | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
nasopharynx | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
nose | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
placenta | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
spinal column | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
GO_0034080 | Biological process | CENP-A containing chromatin assembly |
GO_0007059 | Biological process | chromosome segregation |
GO_0005654 | Cellular component | nucleoplasm |
GO_0005829 | Cellular component | cytosol |
GO_0000939 | Cellular component | inner kinetochore |
GO_0005634 | Cellular component | nucleus |
Gene name | CENPN |
Protein name | Centromere protein N Centromere protein N (CENP-N) (Interphase centromere complex protein 32) |
Synonyms | BM-309 ICEN32 C16orf60 |
Description | FUNCTION: Component of the CENPA-NAC (nucleosome-associated) complex, a complex that plays a central role in assembly of kinetochore proteins, mitotic progression and chromosome segregation. The CENPA-NAC complex recruits the CENPA-CAD (nucleosome distal) complex and may be involved in incorporation of newly synthesized CENPA into centromeres. CENPN is the first protein to bind specifically to CENPA nucleosomes and the direct binding of CENPA nucleosomes by CENPN is required for centromere assembly. Required for chromosome congression and efficiently align the chromosomes on a metaphase plate. . |
Accessions | ENST00000305850.10 [Q96H22-1] ENST00000393335.7 [Q96H22-3] Q96H22 ENST00000439957.7 [Q96H22-4] ENST00000709374.1 [Q96H22-5] H3BMC7 H3BRU7 ENST00000428963.6 [Q96H22-5] H3BMD5 ENST00000709372.1 [Q96H22-3] ENST00000564669.5 ENST00000709370.1 [Q96H22-2] ENST00000568445.1 ENST00000562943.1 ENST00000709369.1 [Q96H22-1] ENST00000299572.9 [Q96H22-2] ENST00000709371.1 [Q96H22-4] |