CDK5R2 report

I. Expression across cell types

II. Expression across tissues

sc-RNAseq data

Insufficient scRNA-seq data for expression of CDK5R2 at tissue level.

III. Associated gene sets

GO_0021766Biological processhippocampus development
GO_0000079Biological processregulation of cyclin-dependent protein serine/threonine kinase activity
GO_0021819Biological processlayer formation in cerebral cortex
GO_0001764Biological processneuron migration
GO_0021722Biological processsuperior olivary nucleus maturation
GO_0045956Biological processpositive regulation of calcium ion-dependent exocytosis
GO_0021549Biological processcerebellum development
GO_0007420Biological processbrain development
GO_0007411Biological processaxon guidance
GO_0016533Cellular componentprotein kinase 5 complex
GO_0005886Cellular componentplasma membrane
GO_0016020Cellular componentmembrane
GO_0043005Cellular componentneuron projection
GO_0000307Cellular componentcyclin-dependent protein kinase holoenzyme complex
GO_0030426Cellular componentgrowth cone
GO_0005737Cellular componentcytoplasm
GO_0061575Molecular functioncyclin-dependent protein serine/threonine kinase activator activity
GO_0008289Molecular functionlipid binding
GO_0019901Molecular functionprotein kinase binding
GO_0003779Molecular functionactin binding

IV. Literature review

[source]
Gene nameCDK5R2
Protein nameCyclin-dependent kinase 5 activator 2 (CDK5 activator 2) (Cyclin-dependent kinase 5 regulatory subunit 2) (p39) (p39I)
Cyclin-dependent kinase 5 activator
SynonymsNCK5AI
DescriptionFUNCTION: Activator of CDK5/TPKII.

AccessionsENST00000302625.6
Q13319
Q5XKD4