CDCA2 report

I. Expression across cell types

Insufficient scRNA-seq data for expression of CDCA2 at single-cell level.

II. Expression across tissues

sc-RNAseq data

Insufficient scRNA-seq data for expression of CDCA2 at tissue level.

III. Associated gene sets

GO_0051301Biological processcell division
GO_0051983Biological processregulation of chromosome segregation
GO_0007059Biological processchromosome segregation
GO_0035307Biological processpositive regulation of protein dephosphorylation
GO_0007088Biological processregulation of mitotic nuclear division
GO_0005694Cellular componentchromosome
GO_0005654Cellular componentnucleoplasm
GO_0005829Cellular componentcytosol
GO_0005634Cellular componentnucleus

IV. Literature review

[source]
Gene nameCDCA2
Protein nameCell division cycle associated 2
Cell division cycle-associated protein 2 (Recruits PP1 onto mitotic chromatin at anaphase protein) (Repo-Man)
Synonyms
DescriptionFUNCTION: Regulator of chromosome structure during mitosis required for condensin-depleted chromosomes to retain their compact architecture through anaphase. Acts by mediating the recruitment of phopsphatase PP1-gamma subunit (PPP1CC) to chromatin at anaphase and into the following interphase. At anaphase onset, its association with chromatin targets a pool of PPP1CC to dephosphorylate substrates. .

AccessionsE9PEI0
ENST00000380665.3
ENST00000330560.8 [Q69YH5-1]
Q69YH5