CCSAP report

I. Expression across cell types

II. Expression across tissues

III. Associated gene sets

GO_1901673Biological processregulation of mitotic spindle assembly
GO_1990755Biological processmitotic spindle microtubule depolymerization
GO_0051301Biological processcell division
GO_0045995Biological processregulation of embryonic development
GO_0005814Cellular componentcentriole
GO_0005930Cellular componentaxoneme
GO_0061673Cellular componentmitotic spindle astral microtubule
GO_0005813Cellular componentcentrosome
GO_0030424Cellular componentaxon
GO_0005929Cellular componentcilium
GO_0036064Cellular componentciliary basal body
GO_0035869Cellular componentciliary transition zone
GO_0072686Cellular componentmitotic spindle
GO_0005819Cellular componentspindle
GO_0008017Molecular functionmicrotubule binding

IV. Literature review

[source]
Gene nameCCSAP
Protein nameCentriole, cilia and spindle-associated protein
SynonymsCSAP
C1orf96
DescriptionFUNCTION: Plays a role in microtubule (MT) stabilization and this stabilization involves the maintenance of NUMA1 at the spindle poles. Colocalizes with polyglutamylated MTs to promote MT stabilization and regulate bipolar spindle formation in mitosis. Binding of CCSAP to centrosomes and the spindle around centrosomes during mitosis inhibits MT depolymerization, thereby stabilizing the mitotic spindle . May play a role in embryonic development. May be required for proper cilia beating (By similarity). .

AccessionsENST00000366687.5 [Q6IQ19-1]
ENST00000366686.1 [Q6IQ19-2]
ENST00000284617.7 [Q6IQ19-1]
Q6IQ19