CATSPERZ report

I. Expression across cell types

Insufficient scRNA-seq data for expression of CATSPERZ at single-cell level.

II. Expression across tissues

sc-RNAseq data

Insufficient scRNA-seq data for expression of CATSPERZ at tissue level.

III. Associated gene sets

GO_0007283Biological processspermatogenesis
GO_0030317Biological processflagellated sperm motility
GO_0048240Biological processsperm capacitation
GO_0007140Biological processmale meiotic nuclear division
GO_0097228Cellular componentsperm principal piece
GO_0036128Cellular componentCatSper complex
GO_0005737Cellular componentcytoplasm

IV. Literature review

[source]
Gene nameCATSPERZ
Protein nameCatsper channel auxiliary subunit zeta
Cation channel sperm-associated auxiliary subunit zeta (CatSper-zeta) (CatSperzeta) (Testis-expressed protein 40)
SynonymsTEX40
C11orf20
DescriptionFUNCTION: Auxiliary component of the CatSper complex, a complex involved in sperm cell hyperactivation. Sperm cell hyperactivation is needed for sperm motility which is essential late in the preparation of sperm for fertilization. Required for a distribution of the CatSper complex in linear quadrilateral nanodomains along the flagellum, maximizing fertilization inside the mammalian female reproductive tract. Together with EFCAB9, associates with the CatSper channel pore and is required for the two-row structure of each single CatSper channel. .

AccessionsQ9NTU4
ENST00000328404.8
ENST00000539943.1
F5H186