CACNG8 | OmnibusX

Name	Number of supported studies	Average coverage
glutamatergic neuron	10 studies	42% ± 22%	Explore
oligodendrocyte precursor cell	7 studies	21% ± 5%	Explore
GABAergic neuron	6 studies	48% ± 21%	Explore
neuron	4 studies	24% ± 6%	Explore
interneuron	4 studies	41% ± 16%	Explore

Name	Number of supported studies	Average coverage
brain	8 studies	33% ± 20%	Explore

Tissue	GTEx Coverage	GTEx Average TPM	GTEx Number of samples	TCGA Coverage	TCGA Average TPM	TCGA Number of samples
brain	98%	5067.77	2589 / 2642	95%	12.62	667 / 705
skin	27%	252.26	492 / 1809	2%	0.10	10 / 472
pancreas	0%	0	0 / 328	19%	0.52	34 / 178
esophagus	0%	0.14	1 / 1445	13%	0.26	24 / 183
stomach	1%	1.90	3 / 359	12%	0.29	35 / 286
muscle	13%	31.95	101 / 803	0%	0	0 / 0
intestine	0%	0.30	1 / 966	12%	0.23	62 / 527
breast	2%	5.22	10 / 459	6%	0.12	67 / 1118
uterus	0%	0	0 / 170	7%	0.26	30 / 459
adrenal gland	0%	0	0 / 258	7%	0.63	15 / 230
ovary	0%	0	0 / 180	6%	0.12	26 / 430
kidney	1%	3.35	1 / 89	5%	0.11	43 / 901
lung	0%	0	0 / 578	6%	0.15	65 / 1155
bladder	0%	0	0 / 21	4%	0.15	22 / 504
eye	0%	0	0 / 0	4%	0.07	3 / 80
peripheral blood	3%	8.33	30 / 929	0%	0	0 / 0
tonsil	0%	0	0 / 0	2%	0.05	1 / 45
liver	0%	0	0 / 226	2%	0.06	9 / 406
thymus	0%	0.89	2 / 653	1%	0.01	4 / 605
prostate	0%	1.21	1 / 245	0%	0.00	1 / 502
adipose	0%	1.13	6 / 1204	0%	0	0 / 0
blood vessel	0%	1.28	4 / 1335	0%	0	0 / 0
heart	0%	0.27	1 / 861	0%	0	0 / 0
abdomen	0%	0	0 / 0	0%	0	0 / 0
bone marrow	0%	0	0 / 0	0%	0	0 / 0
diaphragm	0%	0	0 / 0	0%	0	0 / 0
gingiva	0%	0	0 / 0	0%	0	0 / 0
lymph node	0%	0	0 / 0	0%	0	0 / 29
nasal cavity	0%	0	0 / 0	0%	0	0 / 0
nasopharynx	0%	0	0 / 0	0%	0	0 / 0
nose	0%	0	0 / 0	0%	0	0 / 0
placenta	0%	0	0 / 0	0%	0	0 / 0
spinal column	0%	0	0 / 0	0%	0	0 / 0
spleen	0%	0	0 / 241	0%	0	0 / 0
ureter	0%	0	0 / 0	0%	0	0 / 1

GO_0051968	Biological process	positive regulation of synaptic transmission, glutamatergic
GO_0019226	Biological process	transmission of nerve impulse
GO_0099590	Biological process	neurotransmitter receptor internalization
GO_0006816	Biological process	calcium ion transport
GO_0098943	Biological process	neurotransmitter receptor transport, postsynaptic endosome to lysosome
GO_0070588	Biological process	calcium ion transmembrane transport
GO_0098970	Biological process	postsynaptic neurotransmitter receptor diffusion trapping
GO_2000311	Biological process	regulation of AMPA receptor activity
GO_0005891	Cellular component	voltage-gated calcium channel complex
GO_0098839	Cellular component	postsynaptic density membrane
GO_0032281	Cellular component	AMPA glutamate receptor complex
GO_0005886	Cellular component	plasma membrane
GO_0014069	Cellular component	postsynaptic density
GO_1990454	Cellular component	L-type voltage-gated calcium channel complex
GO_0030666	Cellular component	endocytic vesicle membrane
GO_0005246	Molecular function	calcium channel regulator activity
GO_0005245	Molecular function	voltage-gated calcium channel activity
GO_0016247	Molecular function	channel regulator activity

Gene name	CACNG8
Protein name	Voltage-dependent calcium channel gamma-8 subunit (Neuronal voltage-gated calcium channel gamma-8 subunit) (Transmembrane AMPAR regulatory protein gamma-8) (TARP gamma-8) Voltage-dependent calcium channel gamma-8 subunit
Synonyms	CACNG6
Description	FUNCTION: Regulates the activity of L-type calcium channels that contain CACNA1C as pore-forming subunit (By similarity). Regulates the trafficking and gating properties of AMPA-selective glutamate receptors (AMPARs). Promotes their targeting to the cell membrane and synapses and modulates their gating properties by slowing their rates of activation, deactivation and desensitization and by mediating their resensitization. Does not show subunit-specific AMPA receptor regulation and regulates all AMPAR subunits. . FUNCTION: Regulates the trafficking and gating properties of AMPA-selective glutamate receptors (AMPARs). Promotes their targeting to the cell membrane and synapses and modulates their gating properties by slowing their rates of activation, deactivation and desensitization and by mediating their resensitization. Does not show subunit-specific AMPA receptor regulation and regulates all AMPAR subunits. .
Accessions	A0A1X7SBR8 ENST00000270458.4 Q8WXS5 ENST00000270458

CACNG8 report