Name | Number of supported studies | Average coverage | |
|---|---|---|---|
| glutamatergic neuron | 12 studies | 66% ± 29% | |
| oligodendrocyte precursor cell | 11 studies | 45% ± 24% | |
| astrocyte | 10 studies | 43% ± 22% | |
| GABAergic neuron | 10 studies | 54% ± 19% | |
| smooth muscle cell | 8 studies | 29% ± 18% | |
| endothelial cell | 6 studies | 41% ± 9% | |
| interneuron | 6 studies | 54% ± 21% | |
| microglial cell | 5 studies | 38% ± 25% | |
| cardiac muscle cell | 5 studies | 44% ± 10% | |
| pericyte | 5 studies | 30% ± 9% | |
| type I pneumocyte | 5 studies | 24% ± 4% | |
| neuron | 4 studies | 34% ± 13% | |
| fibroblast | 4 studies | 22% ± 4% | |
| mesothelial cell | 4 studies | 34% ± 11% | |
| retinal ganglion cell | 4 studies | 59% ± 24% | |
| conventional dendritic cell | 3 studies | 31% ± 16% | |
| GABAergic interneuron | 3 studies | 58% ± 2% | |
| ON-bipolar cell | 3 studies | 30% ± 6% | |
| glycinergic amacrine cell | 3 studies | 69% ± 17% | |
| retinal pigment epithelial cell | 3 studies | 57% ± 15% | |
| dendritic cell | 3 studies | 34% ± 12% |
Tissue | GTEx Coverage | GTEx Average TPM | GTEx Number of samples | TCGA Coverage | TCGA Average TPM | TCGA Number of samples |
|---|---|---|---|---|---|---|
| brain | 95% | 1647.84 | 2505 / 2642 | 85% | 5.86 | 598 / 705 |
| ovary | 98% | 502.58 | 177 / 180 | 78% | 3.52 | 337 / 430 |
| prostate | 85% | 416.47 | 208 / 245 | 63% | 1.32 | 315 / 502 |
| kidney | 85% | 362.71 | 76 / 89 | 58% | 1.58 | 522 / 901 |
| esophagus | 93% | 384.12 | 1351 / 1445 | 48% | 1.81 | 88 / 183 |
| lung | 84% | 354.05 | 484 / 578 | 55% | 2.80 | 640 / 1155 |
| thymus | 63% | 166.56 | 410 / 653 | 55% | 2.05 | 331 / 605 |
| adrenal gland | 25% | 168.67 | 65 / 258 | 87% | 47.59 | 200 / 230 |
| muscle | 100% | 1270.20 | 803 / 803 | 0% | 0 | 0 / 0 |
| heart | 94% | 1525.96 | 806 / 861 | 0% | 0 | 0 / 0 |
| stomach | 73% | 241.74 | 263 / 359 | 18% | 0.32 | 51 / 286 |
| tonsil | 0% | 0 | 0 / 0 | 84% | 3.30 | 38 / 45 |
| intestine | 63% | 298.54 | 610 / 966 | 12% | 0.28 | 65 / 527 |
| uterus | 24% | 65.72 | 41 / 170 | 51% | 2.59 | 232 / 459 |
| breast | 36% | 90.31 | 166 / 459 | 30% | 1.09 | 330 / 1118 |
| spleen | 63% | 159.06 | 152 / 241 | 0% | 0 | 0 / 0 |
| blood vessel | 55% | 214.24 | 738 / 1335 | 0% | 0 | 0 / 0 |
| adipose | 55% | 153.47 | 659 / 1204 | 0% | 0 | 0 / 0 |
| pancreas | 0% | 0 | 0 / 328 | 52% | 1.77 | 92 / 178 |
| lymph node | 0% | 0 | 0 / 0 | 45% | 1.37 | 13 / 29 |
| bladder | 14% | 32.00 | 3 / 21 | 27% | 1.27 | 137 / 504 |
| skin | 24% | 55.41 | 434 / 1809 | 10% | 0.44 | 47 / 472 |
| peripheral blood | 12% | 29.57 | 108 / 929 | 0% | 0 | 0 / 0 |
| liver | 0% | 0 | 0 / 226 | 11% | 0.53 | 46 / 406 |
| eye | 0% | 0 | 0 / 0 | 1% | 0.05 | 1 / 80 |
| abdomen | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| bone marrow | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| diaphragm | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| gingiva | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| nasal cavity | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| nasopharynx | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| nose | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| placenta | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| spinal column | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| ureter | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 1 |
| GO_0070588 | Biological process | calcium ion transmembrane transport |
| GO_0005891 | Cellular component | voltage-gated calcium channel complex |
| GO_0046872 | Molecular function | metal ion binding |
| GO_0005245 | Molecular function | voltage-gated calcium channel activity |
| Gene name | CACNA2D3 |
| Protein name | Calcium voltage-gated channel auxiliary subunit alpha2delta 3 (cDNA FLJ56999, highly similar to Homo sapiens calcium channel, voltage-dependent, alpha 2/delta 3 subunit, mRNA) Voltage-dependent calcium channel subunit alpha-2/delta-3 (Voltage-gated calcium channel subunit alpha-2/delta-3) [Cleaved into: Voltage-dependent calcium channel subunit alpha-2-3; Voltage-dependent calcium channel subunit delta-3] Calcium voltage-gated channel auxiliary subunit alpha2delta 3 |
| Synonyms | |
| Description | FUNCTION: The alpha-2/delta subunit of voltage-dependent calcium channels regulates calcium current density and activation/inactivation kinetics of the calcium channel. Acts as a regulatory subunit for P/Q-type calcium channel (CACNA1A), N-type (CACNA1B), L-type (CACNA1C OR CACNA1D) but not T-type (CACNA1G) (By similarity). . |
| Accessions | ENST00000490478.5 [Q8IZS8-2] ENST00000471363.5 [Q8IZS8-3] ENST00000477024.5 ENST00000474759.6 [Q8IZS8-1] F8WAV4 B4DSF6 ENST00000492460.5 C9JAV5 Q8IZS8 ENST00000468658.1 |