CA5A | OmnibusX

Name	Number of supported studies	Average coverage
hepatocyte	3 studies	53% ± 17%	Explore

sc-RNAseq data

Insufficient scRNA-seq data for expression of CA5A at tissue level.

Tissue	GTEx Coverage	GTEx Average TPM	GTEx Number of samples	TCGA Coverage	TCGA Average TPM	TCGA Number of samples
liver	100%	1784.79	226 / 226	84%	18.79	342 / 406
brain	98%	28.31	2601 / 2642	19%	0.35	137 / 705
ovary	72%	5.64	129 / 180	1%	0.02	5 / 430
thymus	52%	2.94	341 / 653	19%	0.42	112 / 605
lung	47%	2.52	269 / 578	4%	0.21	47 / 1155
heart	45%	4.77	384 / 861	0%	0	0 / 0
peripheral blood	44%	4.58	412 / 929	0%	0	0 / 0
adrenal gland	44%	2.24	113 / 258	0%	0.01	1 / 230
spleen	43%	3.16	103 / 241	0%	0	0 / 0
kidney	29%	1.64	26 / 89	2%	0.06	20 / 901
pancreas	28%	1.27	91 / 328	0%	0	0 / 178
prostate	27%	1.29	67 / 245	0%	0	0 / 502
blood vessel	25%	1.21	337 / 1335	0%	0	0 / 0
adipose	24%	1.28	293 / 1204	0%	0	0 / 0
uterus	23%	1.03	39 / 170	1%	0.01	4 / 459
breast	24%	1.23	108 / 459	0%	0.01	2 / 1118
skin	21%	0.93	379 / 1809	0%	0	0 / 472
intestine	18%	0.72	176 / 966	1%	0.03	4 / 527
lymph node	0%	0	0 / 0	17%	0.38	5 / 29
muscle	16%	0.72	130 / 803	0%	0	0 / 0
stomach	14%	0.62	50 / 359	1%	0.03	2 / 286
esophagus	12%	0.47	170 / 1445	1%	0.01	1 / 183
bladder	0%	0	0 / 21	1%	0.03	5 / 504
abdomen	0%	0	0 / 0	0%	0	0 / 0
bone marrow	0%	0	0 / 0	0%	0	0 / 0
diaphragm	0%	0	0 / 0	0%	0	0 / 0
eye	0%	0	0 / 0	0%	0	0 / 80
gingiva	0%	0	0 / 0	0%	0	0 / 0
nasal cavity	0%	0	0 / 0	0%	0	0 / 0
nasopharynx	0%	0	0 / 0	0%	0	0 / 0
nose	0%	0	0 / 0	0%	0	0 / 0
placenta	0%	0	0 / 0	0%	0	0 / 0
spinal column	0%	0	0 / 0	0%	0	0 / 0
tonsil	0%	0	0 / 0	0%	0	0 / 45
ureter	0%	0	0 / 0	0%	0	0 / 1

GO_0006730	Biological process	one-carbon metabolic process
GO_0005737	Cellular component	cytoplasm
GO_0005759	Cellular component	mitochondrial matrix
GO_0005739	Cellular component	mitochondrion
GO_0008270	Molecular function	zinc ion binding
GO_0004089	Molecular function	carbonate dehydratase activity

Gene name	CA5A
Protein name	Carbonic anhydrase 5A, mitochondrial (EC 4.2.1.1) (Carbonate dehydratase VA) (Carbonic anhydrase VA) (CA-VA) Carbonic anhydrase 5A Carbonic anhydrase (EC 4.2.1.1)
Synonyms	CA5
Description	FUNCTION: Mitochondrial carbonic anhydrase that catalyzes the reversible conversion of carbon dioxide to bicarbonate/HCO3 . Mitochondria are impermeable to HCO3, and thus this intramitochondrial carbonic anhydrase is pivotal in providing HCO3 for multiple mitochondrial enzymes that catalyze the formation of essential metabolites of intermediary metabolism in the urea and Krebs cycles . . FUNCTION: Reversible hydration of carbon dioxide. . FUNCTION: Reversible hydration of carbon dioxide. .
Accessions	ENST00000649158.1 A0A3B3IRX9 P35218 A0A3B3ITA6 ENST00000649794.3 ENST00000648177.1 ENST00000648022.1 A0A3B3ITU9

CA5A report