BHMT | OmnibusX

Name	Number of supported studies	Average coverage
epithelial cell of proximal tubule	9 studies	45% ± 13%	Explore
hepatocyte	6 studies	58% ± 21%	Explore

Name	Number of supported studies	Average coverage
kidney	4 studies	25% ± 13%	Explore
liver	3 studies	38% ± 9%	Explore

Tissue	GTEx Coverage	GTEx Average TPM	GTEx Number of samples	TCGA Coverage	TCGA Average TPM	TCGA Number of samples
liver	100%	28483.92	226 / 226	84%	201.15	340 / 406
kidney	100%	16037.85	89 / 89	79%	136.97	712 / 901
bladder	95%	1114.14	20 / 21	25%	29.91	127 / 504
ureter	0%	0	0 / 0	100%	26.43	1 / 1
stomach	99%	178.69	355 / 359	1%	0.07	2 / 286
adrenal gland	87%	36.15	225 / 258	9%	1.57	21 / 230
thymus	92%	55.90	598 / 653	0%	0	0 / 605
adipose	86%	66.90	1036 / 1204	0%	0	0 / 0
breast	80%	53.26	368 / 459	0%	0	0 / 1118
prostate	78%	34.67	191 / 245	0%	0	0 / 502
esophagus	72%	173.80	1035 / 1445	1%	0.03	1 / 183
intestine	67%	50.70	652 / 966	1%	0.24	4 / 527
blood vessel	57%	18.96	761 / 1335	0%	0	0 / 0
uterus	51%	21.51	86 / 170	2%	1.59	11 / 459
brain	49%	22.74	1285 / 2642	0%	0	0 / 705
ovary	48%	14.36	87 / 180	0%	0.08	1 / 430
lung	33%	7.97	188 / 578	1%	0.64	11 / 1155
skin	30%	9.20	540 / 1809	0%	0.06	2 / 472
heart	24%	6.87	209 / 861	0%	0	0 / 0
pancreas	12%	2.54	38 / 328	5%	3.62	9 / 178
peripheral blood	16%	22.94	153 / 929	0%	0	0 / 0
muscle	10%	2.38	77 / 803	0%	0	0 / 0
spleen	4%	9.90	9 / 241	0%	0	0 / 0
tonsil	0%	0	0 / 0	2%	0.38	1 / 45
abdomen	0%	0	0 / 0	0%	0	0 / 0
bone marrow	0%	0	0 / 0	0%	0	0 / 0
diaphragm	0%	0	0 / 0	0%	0	0 / 0
eye	0%	0	0 / 0	0%	0	0 / 80
gingiva	0%	0	0 / 0	0%	0	0 / 0
lymph node	0%	0	0 / 0	0%	0	0 / 29
nasal cavity	0%	0	0 / 0	0%	0	0 / 0
nasopharynx	0%	0	0 / 0	0%	0	0 / 0
nose	0%	0	0 / 0	0%	0	0 / 0
placenta	0%	0	0 / 0	0%	0	0 / 0
spinal column	0%	0	0 / 0	0%	0	0 / 0

GO_0046500	Biological process	S-adenosylmethionine metabolic process
GO_0071267	Biological process	L-methionine salvage
GO_0006479	Biological process	protein methylation
GO_0006579	Biological process	amino-acid betaine catabolic process
GO_0050666	Biological process	regulation of homocysteine metabolic process
GO_0071266	Biological process	'de novo' L-methionine biosynthetic process
GO_0006577	Biological process	amino-acid betaine metabolic process
GO_0070062	Cellular component	extracellular exosome
GO_0005829	Cellular component	cytosol
GO_0005634	Cellular component	nucleus
GO_0008270	Molecular function	zinc ion binding
GO_0047150	Molecular function	betaine-homocysteine S-methyltransferase activity

Gene name	BHMT
Protein name	Betaine--homocysteine S-methyltransferase 1 (EC 2.1.1.5)
Synonyms	hCG_2039815 HEL-S-61p
Description	FUNCTION: Involved in the regulation of homocysteine metabolism. Converts betaine and homocysteine to dimethylglycine and methionine, respectively. This reaction is also required for the irreversible oxidation of choline. . FUNCTION: Involved in the regulation of homocysteine metabolism. Converts betaine and homocysteine to dimethylglycine and methionine, respectively. This reaction is also required for the irreversible oxidation of choline. . FUNCTION: Involved in the regulation of homocysteine metabolism. Converts betaine and homocysteine to dimethylglycine and methionine, respectively. This reaction is also required for the irreversible oxidation of choline. .
Accessions	ENST00000524080.1 V9HWA4 Q93088 ENST00000274353.10 E5RJH0

BHMT report