Name | Number of supported studies | Average coverage | |
---|---|---|---|
ciliated cell | 6 studies | 30% ± 11% |
Insufficient scRNA-seq data for expression of BEST4 at tissue level.
Tissue | GTEx Coverage | GTEx Average TPM | GTEx Number of samples | TCGA Coverage | TCGA Average TPM | TCGA Number of samples |
---|---|---|---|---|---|---|
ovary | 93% | 59.73 | 167 / 180 | 89% | 4.31 | 383 / 430 |
thymus | 96% | 72.47 | 627 / 653 | 80% | 2.38 | 487 / 605 |
adrenal gland | 100% | 198.52 | 258 / 258 | 56% | 1.36 | 128 / 230 |
uterus | 96% | 141.31 | 163 / 170 | 56% | 1.70 | 259 / 459 |
brain | 93% | 191.24 | 2447 / 2642 | 48% | 1.75 | 335 / 705 |
intestine | 86% | 1491.68 | 835 / 966 | 51% | 1.56 | 267 / 527 |
lung | 88% | 214.45 | 509 / 578 | 48% | 1.24 | 559 / 1155 |
kidney | 74% | 50.48 | 66 / 89 | 58% | 2.57 | 520 / 901 |
bladder | 71% | 30.19 | 15 / 21 | 54% | 1.44 | 272 / 504 |
pancreas | 39% | 14.68 | 129 / 328 | 64% | 2.00 | 114 / 178 |
ureter | 0% | 0 | 0 / 0 | 100% | 1.72 | 1 / 1 |
esophagus | 65% | 35.15 | 944 / 1445 | 34% | 1.00 | 63 / 183 |
breast | 71% | 54.68 | 326 / 459 | 27% | 0.59 | 305 / 1118 |
lymph node | 0% | 0 | 0 / 0 | 97% | 2.94 | 28 / 29 |
spleen | 92% | 51.15 | 221 / 241 | 0% | 0 | 0 / 0 |
prostate | 83% | 43.31 | 203 / 245 | 3% | 0.05 | 16 / 502 |
skin | 73% | 76.39 | 1313 / 1809 | 10% | 0.18 | 47 / 472 |
blood vessel | 78% | 48.09 | 1039 / 1335 | 0% | 0 | 0 / 0 |
liver | 52% | 26.95 | 117 / 226 | 16% | 0.36 | 65 / 406 |
stomach | 21% | 7.10 | 77 / 359 | 40% | 1.11 | 115 / 286 |
adipose | 57% | 25.92 | 692 / 1204 | 0% | 0 | 0 / 0 |
peripheral blood | 56% | 28.99 | 519 / 929 | 0% | 0 | 0 / 0 |
heart | 30% | 11.09 | 262 / 861 | 0% | 0 | 0 / 0 |
tonsil | 0% | 0 | 0 / 0 | 18% | 0.40 | 8 / 45 |
muscle | 6% | 2.74 | 52 / 803 | 0% | 0 | 0 / 0 |
abdomen | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
bone marrow | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
diaphragm | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
eye | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 80 |
gingiva | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
nasal cavity | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
nasopharynx | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
nose | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
placenta | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
spinal column | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
GO_0015701 | Biological process | bicarbonate transport |
GO_1902476 | Biological process | chloride transmembrane transport |
GO_0008150 | Biological process | biological_process |
GO_0034707 | Cellular component | chloride channel complex |
GO_0005886 | Cellular component | plasma membrane |
GO_0005254 | Molecular function | chloride channel activity |
GO_0160133 | Molecular function | bicarbonate channel activity |
GO_0005229 | Molecular function | intracellularly calcium-gated chloride channel activity |
GO_0046872 | Molecular function | metal ion binding |
GO_0003674 | Molecular function | molecular_function |
Gene name | BEST4 |
Protein name | Bestrophin-4 (Vitelliform macular dystrophy 2-like protein 2) |
Synonyms | VMD2L2 |
Description | FUNCTION: Forms calcium-sensitive chloride channels. Permeable to bicarbonate. . |
Accessions | ENST00000372207.4 Q8NFU0 |