BEST4 report

I. Expression across cell types

II. Expression across tissues

sc-RNAseq data

Insufficient scRNA-seq data for expression of BEST4 at tissue level.

III. Associated gene sets

GO_0015701Biological processbicarbonate transport
GO_1902476Biological processchloride transmembrane transport
GO_0008150Biological processbiological_process
GO_0034707Cellular componentchloride channel complex
GO_0005886Cellular componentplasma membrane
GO_0005254Molecular functionchloride channel activity
GO_0160133Molecular functionbicarbonate channel activity
GO_0005229Molecular functionintracellularly calcium-gated chloride channel activity
GO_0046872Molecular functionmetal ion binding
GO_0003674Molecular functionmolecular_function

IV. Literature review

[source]
Gene nameBEST4
Protein nameBestrophin-4 (Vitelliform macular dystrophy 2-like protein 2)
SynonymsVMD2L2
DescriptionFUNCTION: Forms calcium-sensitive chloride channels. Permeable to bicarbonate. .

AccessionsENST00000372207.4
Q8NFU0