BEST3 | OmnibusX

Name	Number of supported studies	Average coverage
oligodendrocyte precursor cell	6 studies	37% ± 9%	Explore
precursor B cell	3 studies	30% ± 10%	Explore

sc-RNAseq data

Insufficient scRNA-seq data for expression of BEST3 at tissue level.

Tissue	GTEx Coverage	GTEx Average TPM	GTEx Number of samples	TCGA Coverage	TCGA Average TPM	TCGA Number of samples
brain	92%	286.66	2429 / 2642	96%	19.71	678 / 705
muscle	100%	4871.46	803 / 803	0%	0	0 / 0
adrenal gland	62%	63.47	159 / 258	10%	0.38	22 / 230
prostate	44%	87.15	107 / 245	22%	0.41	109 / 502
kidney	6%	4.76	5 / 89	9%	0.14	85 / 901
breast	12%	15.17	55 / 459	3%	0.08	31 / 1118
skin	13%	17.72	229 / 1809	1%	0.01	3 / 472
pancreas	8%	6.13	25 / 328	4%	0.08	8 / 178
tonsil	0%	0	0 / 0	9%	0.22	4 / 45
lymph node	0%	0	0 / 0	7%	0.22	2 / 29
stomach	0%	0	0 / 359	6%	0.55	18 / 286
heart	5%	4.96	45 / 861	0%	0	0 / 0
bladder	0%	0	0 / 21	5%	0.46	24 / 504
esophagus	1%	4.25	13 / 1445	4%	0.12	7 / 183
uterus	0%	0	0 / 170	5%	0.46	21 / 459
intestine	0%	0.12	1 / 966	4%	0.19	22 / 527
thymus	1%	2.54	7 / 653	3%	0.05	16 / 605
lung	0%	0	0 / 578	3%	0.17	38 / 1155
liver	0%	0	0 / 226	2%	0.03	9 / 406
peripheral blood	2%	1.79	18 / 929	0%	0	0 / 0
adipose	1%	1.23	11 / 1204	0%	0	0 / 0
ovary	0%	0	0 / 180	1%	0.01	3 / 430
blood vessel	0%	3.73	6 / 1335	0%	0	0 / 0
abdomen	0%	0	0 / 0	0%	0	0 / 0
bone marrow	0%	0	0 / 0	0%	0	0 / 0
diaphragm	0%	0	0 / 0	0%	0	0 / 0
eye	0%	0	0 / 0	0%	0	0 / 80
gingiva	0%	0	0 / 0	0%	0	0 / 0
nasal cavity	0%	0	0 / 0	0%	0	0 / 0
nasopharynx	0%	0	0 / 0	0%	0	0 / 0
nose	0%	0	0 / 0	0%	0	0 / 0
placenta	0%	0	0 / 0	0%	0	0 / 0
spinal column	0%	0	0 / 0	0%	0	0 / 0
spleen	0%	0	0 / 241	0%	0	0 / 0
ureter	0%	0	0 / 0	0%	0	0 / 1

GO_1902476	Biological process	chloride transmembrane transport
GO_0008150	Biological process	biological_process
GO_0043271	Biological process	negative regulation of monoatomic ion transport
GO_0034707	Cellular component	chloride channel complex
GO_0005886	Cellular component	plasma membrane
GO_0099095	Molecular function	ligand-gated monoatomic anion channel activity
GO_0005229	Molecular function	intracellularly calcium-gated chloride channel activity
GO_0046872	Molecular function	metal ion binding
GO_0003674	Molecular function	molecular_function

Gene name	BEST3
Protein name	Bestrophin Bestrophin-3 (Vitelliform macular dystrophy 2-like protein 3)
Synonyms	VMD2L3
Description	FUNCTION: Forms calcium-sensitive chloride channels. Permeable to bicarbonate. . FUNCTION: Forms calcium-sensitive chloride channels. Permeable to bicarbonate. . FUNCTION: Forms calcium-sensitive chloride channels. Permeable to bicarbonate. . FUNCTION: Forms calcium-sensitive chloride channels. Permeable to bicarbonate. . FUNCTION: Forms calcium-sensitive chloride channels. Permeable to bicarbonate. .
Accessions	ENST00000266661.8 [Q8N1M1-4] F8VR37 Q8N1M1 ENST00000476098.5 ENST00000553096.5 [Q8N1M1-6] F8VVX2 F8VZR0 ENST00000488961.5 [Q8N1M1-5] ENST00000551160.5 [Q8N1M1-4] ENST00000547208.5 ENST00000548658.1 ENST00000330891.10 [Q8N1M1-2] E9PNM2 ENST00000552295.5 ENST00000331471.8 [Q8N1M1-1]

BEST3 report