BEST1 | OmnibusX

Name	Number of supported studies	Average coverage
macrophage	9 studies	28% ± 11%	Explore
oligodendrocyte	6 studies	29% ± 12%	Explore
non-classical monocyte	5 studies	20% ± 6%	Explore
retinal pigment epithelial cell	4 studies	82% ± 13%	Explore
neutrophil	3 studies	39% ± 7%	Explore
conventional dendritic cell	3 studies	16% ± 1%	Explore
monocyte	3 studies	27% ± 4%	Explore
astrocyte	3 studies	25% ± 2%	Explore

Name	Number of supported studies	Average coverage
brain	4 studies	29% ± 8%	Explore

Tissue	GTEx Coverage	GTEx Average TPM	GTEx Number of samples	TCGA Coverage	TCGA Average TPM	TCGA Number of samples
brain	97%	2181.52	2573 / 2642	100%	11.36	704 / 705
skin	78%	538.94	1417 / 1809	97%	18.42	460 / 472
breast	99%	1053.82	453 / 459	59%	1.11	659 / 1118
lung	100%	2157.65	576 / 578	53%	0.97	613 / 1155
adrenal gland	90%	690.15	233 / 258	55%	1.11	127 / 230
thymus	84%	572.54	546 / 653	54%	0.86	328 / 605
ovary	99%	929.61	178 / 180	36%	0.56	153 / 430
kidney	67%	581.91	60 / 89	66%	1.88	594 / 901
prostate	92%	833.84	225 / 245	34%	0.47	169 / 502
intestine	94%	767.08	906 / 966	30%	0.49	157 / 527
uterus	98%	983.66	166 / 170	24%	0.44	109 / 459
bladder	90%	1247.00	19 / 21	22%	0.37	111 / 504
esophagus	85%	664.46	1224 / 1445	26%	0.45	48 / 183
stomach	66%	465.70	238 / 359	34%	0.60	98 / 286
eye	0%	0	0 / 0	100%	10.46	80 / 80
spleen	100%	2304.44	241 / 241	0%	0	0 / 0
adipose	100%	1552.73	1202 / 1204	0%	0	0 / 0
peripheral blood	87%	3903.07	804 / 929	0%	0	0 / 0
pancreas	28%	147.99	91 / 328	53%	0.94	95 / 178
lymph node	0%	0	0 / 0	72%	1.21	21 / 29
heart	70%	571.16	602 / 861	0%	0	0 / 0
blood vessel	69%	542.85	918 / 1335	0%	0	0 / 0
liver	28%	162.54	63 / 226	19%	0.42	76 / 406
tonsil	0%	0	0 / 0	13%	0.21	6 / 45
muscle	8%	39.20	62 / 803	0%	0	0 / 0
abdomen	0%	0	0 / 0	0%	0	0 / 0
bone marrow	0%	0	0 / 0	0%	0	0 / 0
diaphragm	0%	0	0 / 0	0%	0	0 / 0
gingiva	0%	0	0 / 0	0%	0	0 / 0
nasal cavity	0%	0	0 / 0	0%	0	0 / 0
nasopharynx	0%	0	0 / 0	0%	0	0 / 0
nose	0%	0	0 / 0	0%	0	0 / 0
placenta	0%	0	0 / 0	0%	0	0 / 0
spinal column	0%	0	0 / 0	0%	0	0 / 0
ureter	0%	0	0 / 0	0%	0	0 / 1

GO_0007601	Biological process	visual perception
GO_0006821	Biological process	chloride transport
GO_0051924	Biological process	regulation of calcium ion transport
GO_0034220	Biological process	monoatomic ion transmembrane transport
GO_0051259	Biological process	protein complex oligomerization
GO_0048167	Biological process	regulation of synaptic plasticity
GO_0050908	Biological process	detection of light stimulus involved in visual perception
GO_1902476	Biological process	chloride transmembrane transport
GO_0030321	Biological process	transepithelial chloride transport
GO_0061534	Biological process	gamma-aminobutyric acid secretion, neurotransmission
GO_0015701	Biological process	bicarbonate transport
GO_0014047	Biological process	glutamate secretion
GO_0098793	Cellular component	presynapse
GO_0005886	Cellular component	plasma membrane
GO_0016020	Cellular component	membrane
GO_0098857	Cellular component	membrane microdomain
GO_0009925	Cellular component	basal plasma membrane
GO_0005829	Cellular component	cytosol
GO_0034707	Cellular component	chloride channel complex
GO_0016323	Cellular component	basolateral plasma membrane
GO_0160133	Molecular function	bicarbonate channel activity
GO_0042802	Molecular function	identical protein binding
GO_0015106	Molecular function	bicarbonate transmembrane transporter activity
GO_0005229	Molecular function	intracellularly calcium-gated chloride channel activity
GO_0022834	Molecular function	ligand-gated channel activity
GO_0005254	Molecular function	chloride channel activity

Gene name	BEST1
Protein name	Bestrophin Bestrophin 1 Bestrophin 1 isoform 8 Bestrophin-1 (TU15B) (Vitelliform macular dystrophy protein 2)
Synonyms	hCG_40845 VMD2
Description	FUNCTION: Forms calcium-sensitive chloride channels. Highly permeable to bicarbonate. . FUNCTION: Forms calcium-sensitive chloride channels. Permeable to bicarbonate. . FUNCTION: Forms calcium-sensitive chloride channels. Permeable to bicarbonate. . FUNCTION: Forms calcium-sensitive chloride channels. Permeable to bicarbonate. . FUNCTION: Forms calcium-sensitive chloride channels. Permeable to bicarbonate. . FUNCTION: Forms calcium-sensitive chloride channels. Permeable to bicarbonate. . FUNCTION: Forms calcium-sensitive chloride channels. Permeable to bicarbonate. .
Accessions	A0A0S2Z579 ENST00000449131.6 [O76090-3] A0A0S2Z4V3 ENST00000524926.5 E9PMB5 A0A0S2Z5F4 A0A0C4DGE9 ENST00000526988.1 O76090 A0A0S2Z4J9 B7Z1N8 A0A0S2Z4M4 ENST00000534553.5 ENST00000378043.9 [O76090-1]

BEST1 report