BCO1 | OmnibusX

Name	Number of supported studies	Average coverage
retinal pigment epithelial cell	4 studies	34% ± 16%	Explore
astrocyte	3 studies	26% ± 8%	Explore

sc-RNAseq data

Insufficient scRNA-seq data for expression of BCO1 at tissue level.

Tissue	GTEx Coverage	GTEx Average TPM	GTEx Number of samples	TCGA Coverage	TCGA Average TPM	TCGA Number of samples
intestine	99%	143.29	958 / 966	90%	4.13	473 / 527
kidney	100%	138.18	89 / 89	89%	10.15	800 / 901
brain	91%	48.56	2404 / 2642	85%	3.19	602 / 705
stomach	90%	36.72	322 / 359	85%	4.57	242 / 286
esophagus	78%	23.48	1131 / 1445	59%	3.03	108 / 183
bladder	86%	24.48	18 / 21	48%	1.78	242 / 504
uterus	86%	34.48	147 / 170	42%	2.13	195 / 459
prostate	99%	64.93	242 / 245	29%	0.56	148 / 502
ovary	99%	87.98	178 / 180	27%	0.91	116 / 430
pancreas	38%	5.51	124 / 328	82%	3.47	146 / 178
liver	96%	49.88	216 / 226	22%	0.64	89 / 406
lung	51%	8.73	295 / 578	44%	1.97	504 / 1155
skin	67%	20.20	1215 / 1809	3%	0.06	12 / 472
breast	57%	11.66	263 / 459	9%	0.21	101 / 1118
thymus	60%	12.38	394 / 653	6%	0.12	34 / 605
tonsil	0%	0	0 / 0	38%	0.87	17 / 45
adipose	35%	5.61	419 / 1204	0%	0	0 / 0
muscle	28%	5.56	228 / 803	0%	0	0 / 0
peripheral blood	17%	21.51	155 / 929	0%	0	0 / 0
heart	12%	1.38	101 / 861	0%	0	0 / 0
adrenal gland	5%	0.53	12 / 258	2%	0.05	5 / 230
blood vessel	7%	0.82	88 / 1335	0%	0	0 / 0
eye	0%	0	0 / 0	4%	0.20	3 / 80
spleen	2%	0.17	4 / 241	0%	0	0 / 0
abdomen	0%	0	0 / 0	0%	0	0 / 0
bone marrow	0%	0	0 / 0	0%	0	0 / 0
diaphragm	0%	0	0 / 0	0%	0	0 / 0
gingiva	0%	0	0 / 0	0%	0	0 / 0
lymph node	0%	0	0 / 0	0%	0	0 / 29
nasal cavity	0%	0	0 / 0	0%	0	0 / 0
nasopharynx	0%	0	0 / 0	0%	0	0 / 0
nose	0%	0	0 / 0	0%	0	0 / 0
placenta	0%	0	0 / 0	0%	0	0 / 0
spinal column	0%	0	0 / 0	0%	0	0 / 0
ureter	0%	0	0 / 0	0%	0	0 / 1

GO_0035238	Biological process	vitamin A biosynthetic process
GO_0001523	Biological process	retinoid metabolic process
GO_0042574	Biological process	retinal metabolic process
GO_1901810	Biological process	beta-carotene metabolic process
GO_0042572	Biological process	retinol metabolic process
GO_0016121	Biological process	carotene catabolic process
GO_0005829	Cellular component	cytosol
GO_0003834	Molecular function	beta-carotene 15,15'-dioxygenase activity
GO_0010436	Molecular function	carotenoid dioxygenase activity
GO_0046872	Molecular function	metal ion binding

Gene name	BCO1
Protein name	Beta-carotene oxygenase 1 Beta,beta-carotene 15,15'-dioxygenase (EC 1.13.11.63) (Beta-carotene dioxygenase 1) (Beta-carotene oxygenase 1)
Synonyms	BCDO BCDO1 BCMO1
Description	FUNCTION: Symmetrically cleaves beta-carotene into two molecules of retinal using a dioxygenase mechanism. .
Accessions	H3BPA2 Q9HAY6 ENST00000563804.5 ENST00000564552.1 H3BV18 ENST00000258168.7

BCO1 report