B3GNTL1 report

I. Expression across cell types

Insufficient scRNA-seq data for expression of B3GNTL1 at single-cell level.

II. Expression across tissues

sc-RNAseq data

Insufficient scRNA-seq data for expression of B3GNTL1 at tissue level.

III. Associated gene sets

GO_0006400Biological processtRNA modification
GO_0006417Biological processregulation of translation
GO_0005737Cellular componentcytoplasm
GO_0141125Molecular functiontRNA-queuosine(34) galactosyltransferase activity

IV. Literature review

[source]
Gene nameB3GNTL1
Protein nameB3GNTL1 protein (HCG30384, isoform CRA_a)
HCG30384, isoform CRA_d (UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase like 1) (UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase-like protein 1)
HCG30384, isoform CRA_b (UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase like 1) (UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase-like protein 1)
Queuosine-tRNA galactosyltransferase (QTGAL) (EC 2.4.1.-) (Beta-1,3-N-acetylglucosaminyltransferase 8) (BGnT-8) (Beta-1,3-Gn-T8) (Beta3Gn-T8) (UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase-like protein 1) (BGnT-like protein 1) (Beta1,3-N-acetylglucosaminyltransferase-like protein 1) (Beta3Gn-T-like protein 1) (Beta3GnTL1)
UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase like 1 (UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase-like protein 1)
SynonymshCG_30384
QTGAL
B3GNT8
DescriptionFUNCTION: Glycosyltransferase that specifically catalyzes galactosylation of cytoplasmic tRNA(Tyr) modified with queuosine at position 34 (queuosine(34)) . Galactosylates the cyclopentene hydroxyl group of queuosine(34) in tRNA(Tyr) to form galactosyl-queuosine(34) . Mannosylation of queuosine(34) in tRNA(Tyr) is required to slow-down elongation at cognate codons UAC and suppress stop codon readthrough, thereby regulating protein translation . .

AccessionsENST00000632023.1
ENST00000633139.1
Q67FW5
ENST00000571218.1
Q2TB72
I3L232
ENST00000632715.1
ENST00000572977.5
I3L4B6
ENST00000576599.5
ENST00000621596.2
I3L1A1
ENST00000320865.4