I. Expression across cell types
Name | Number of supported studies  | Average coverage | |
|---|---|---|---|
| goblet cell | 3 studies | 43% ± 18% |
Name | Number of supported studies | Average coverage | |
|---|---|---|---|
| goblet cell | 3 studies | 43% ± 18% |
Insufficient scRNA-seq data for expression of B3GNT6 at tissue level.
Tissue | GTEx Coverage | GTEx Average TPM | GTEx Number of samples | TCGA Coverage | TCGA Average TPM | TCGA Number of samples |
|---|---|---|---|---|---|---|
| stomach | 67% | 425.03 | 242 / 359 | 43% | 15.09 | 124 / 286 |
| intestine | 52% | 575.02 | 505 / 966 | 57% | 19.75 | 301 / 527 |
| esophagus | 35% | 135.51 | 499 / 1445 | 30% | 8.29 | 54 / 183 |
| pancreas | 1% | 1.39 | 4 / 328 | 50% | 15.43 | 89 / 178 |
| prostate | 4% | 1.51 | 9 / 245 | 44% | 18.10 | 222 / 502 |
| lung | 5% | 4.06 | 29 / 578 | 36% | 12.30 | 411 / 1155 |
| bladder | 0% | 0 | 0 / 21 | 18% | 5.75 | 91 / 504 |
| tonsil | 0% | 0 | 0 / 0 | 11% | 0.94 | 5 / 45 |
| uterus | 0% | 0 | 0 / 170 | 4% | 0.27 | 18 / 459 |
| thymus | 0% | 0.04 | 1 / 653 | 1% | 0.06 | 6 / 605 |
| breast | 1% | 2.20 | 3 / 459 | 0% | 0.01 | 4 / 1118 |
| liver | 0% | 0 | 0 / 226 | 1% | 0.09 | 4 / 406 |
| spleen | 1% | 0.66 | 2 / 241 | 0% | 0 | 0 / 0 |
| ovary | 0% | 0 | 0 / 180 | 0% | 0.02 | 2 / 430 |
| adrenal gland | 0% | 0.44 | 1 / 258 | 0% | 0 | 0 / 230 |
| muscle | 0% | 0.27 | 3 / 803 | 0% | 0 | 0 / 0 |
| adipose | 0% | 0.49 | 4 / 1204 | 0% | 0 | 0 / 0 |
| skin | 0% | 0.03 | 1 / 1809 | 0% | 0.00 | 1 / 472 |
| brain | 0% | 0.07 | 6 / 2642 | 0% | 0 | 0 / 705 |
| blood vessel | 0% | 0.07 | 2 / 1335 | 0% | 0 | 0 / 0 |
| heart | 0% | 0.03 | 1 / 861 | 0% | 0 | 0 / 0 |
| peripheral blood | 0% | 0.27 | 1 / 929 | 0% | 0 | 0 / 0 |
| abdomen | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| bone marrow | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| diaphragm | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| eye | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 80 |
| gingiva | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| kidney | 0% | 0 | 0 / 89 | 0% | 0 | 0 / 901 |
| lymph node | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 29 |
| nasal cavity | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| nasopharynx | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| nose | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| placenta | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| spinal column | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| ureter | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 1 |
| GO_0016266 | Biological process | O-glycan processing |
| GO_0016269 | Biological process | O-glycan processing, core 3 |
| GO_0030311 | Biological process | poly-N-acetyllactosamine biosynthetic process |
| GO_0006493 | Biological process | protein O-linked glycosylation |
| GO_0009101 | Biological process | glycoprotein biosynthetic process |
| GO_0000139 | Cellular component | Golgi membrane |
| GO_0016020 | Cellular component | membrane |
| GO_0008194 | Molecular function | UDP-glycosyltransferase activity |
| GO_0008499 | Molecular function | UDP-galactose:beta-N-acetylglucosamine beta-1,3-galactosyltransferase activity |
| GO_0047223 | Molecular function | beta-1,3-galactosyl-O-glycosyl-glycoprotein beta-1,3-N-acetylglucosaminyltransferase activity |
| GO_0008378 | Molecular function | galactosyltransferase activity |
| GO_0047224 | Molecular function | acetylgalactosaminyl-O-glycosyl-glycoprotein beta-1,3-N-acetylglucosaminyltransferase activity |
| Gene name | B3GNT6 |
| Protein name | Acetylgalactosaminyl-O-glycosyl-glycoprotein beta-1,3-N-acetylglucosaminyltransferase (EC 2.4.1.147) (Core 3 synthase) (UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 6) (BGnT-6) (Beta-1,3-Gn-T6) (Beta-1,3-N-acetylglucosaminyltransferase 6) (Beta3Gn-T6) UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 6 |
| Synonyms | |
| Description | FUNCTION: Beta-1,3-N-acetylglucosaminyltransferase that synthesizes the core 3 structure of the O-glycan, an important precursor in the biosynthesis of mucin-type glycoproteins. Plays an important role in the synthesis of mucin-type O-glycans in digestive organs. |
| Accessions | ENST00000528622.5 Q6ZMB0 E9PJ79 ENST00000622824.1 [Q6ZMB0-1] |
