B3GALT2 report

I. Expression across cell types

II. Expression across tissues

sc-RNAseq data

Insufficient scRNA-seq data for expression of B3GALT2 at tissue level.

III. Associated gene sets

GO_0009312Biological processoligosaccharide biosynthetic process
GO_0006493Biological processprotein O-linked glycosylation
GO_0006682Biological processgalactosylceramide biosynthetic process
GO_0006486Biological processprotein glycosylation
GO_0000139Cellular componentGolgi membrane
GO_0008499Molecular functionUDP-galactose:beta-N-acetylglucosamine beta-1,3-galactosyltransferase activity
GO_0047275Molecular functionglucosaminylgalactosylglucosylceramide beta-galactosyltransferase activity

IV. Literature review

[source]
Gene nameB3GALT2
Protein nameBeta-1,3-galactosyltransferase 2 (Beta-1,3-GalTase 2) (Beta3Gal-T2) (Beta3GalT2) (EC 2.4.1.86) (UDP-galactose:2-acetamido-2-deoxy-D-glucose 3beta-galactosyltransferase 2)
Synonyms
DescriptionFUNCTION: Beta-1,3-galactosyltransferase that transfers galactose from UDP-galactose to substrates with a terminal beta-N-acetylglucosamine (beta-GlcNAc) residue. Can also utilize substrates with a terminal galactose residue, albeit with lower efficiency. Involved in the biosynthesis of the carbohydrate moieties of glycolipids and glycoproteins. Inactive towards substrates with terminal alpha-N-acetylglucosamine (alpha-GlcNAc) or alpha-N-acetylgalactosamine (alpha-GalNAc) residues. .

AccessionsO43825
ENST00000367434.5