ATXN3L report

I. Expression across cell types

Insufficient scRNA-seq data for expression of ATXN3L at single-cell level.

II. Expression across tissues

sc-RNAseq data

Insufficient scRNA-seq data for expression of ATXN3L at tissue level.

III. Associated gene sets

GO_0006508Biological processproteolysis
GO_0016579Biological processprotein deubiquitination
GO_0005829Cellular componentcytosol
GO_0005634Cellular componentnucleus
GO_0004843Molecular functioncysteine-type deubiquitinase activity

IV. Literature review

[source]
Gene nameATXN3L
Protein nameAtaxin-3-like protein (EC 3.4.19.12) (Machado-Joseph disease protein 1-like)
SynonymsATX3L
MJDL
DescriptionFUNCTION: Deubiquitinating enzyme that cleaves both 'Lys-48'-linked and 'Lys-63'-linked poly-ubiquitin chains (in vitro) . Acts as a deubiquitinating enzyme for the transcription factor KLF5, playing a role in the regulation of KLF5 stability . .

AccessionsQ9H3M9
ENST00000380622.5