ATP5MGL report

I. Expression across cell types

Insufficient scRNA-seq data for expression of ATP5MGL at single-cell level.

II. Expression across tissues

sc-RNAseq data

Insufficient scRNA-seq data for expression of ATP5MGL at tissue level.

III. Associated gene sets

GO_1902600Biological processproton transmembrane transport
GO_0015986Biological processproton motive force-driven ATP synthesis
GO_0005753Cellular componentmitochondrial proton-transporting ATP synthase complex
GO_0000276Cellular componentmitochondrial proton-transporting ATP synthase complex, coupling factor F(o)
GO_0005743Cellular componentmitochondrial inner membrane
GO_0005739Cellular componentmitochondrion
GO_0046933Molecular functionproton-transporting ATP synthase activity, rotational mechanism

IV. Literature review

[source]
Gene nameATP5MGL
Protein namePutative ATP synthase subunit g 2, mitochondrial (ATPase subunit g 2) (ATP synthase membrane subunit g-like protein)
SynonymsATP5K2
ATP5L2
DescriptionFUNCTION: Mitochondrial membrane ATP synthase (F(1)F(0) ATP synthase or Complex V) produces ATP from ADP in the presence of a proton gradient across the membrane which is generated by electron transport complexes of the respiratory chain. F-type ATPases consist of two structural domains, F(1) - containing the extramembraneous catalytic core, and F(0) - containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation. Part of the complex F(0) domain. Minor subunit located with subunit a in the membrane (By similarity). .

AccessionsQ7Z4Y8
ENST00000505920.1