ATP13A1 | OmnibusX

Name	Number of supported studies	Average coverage
epithelial cell	4 studies	24% ± 6%	Explore
ciliated cell	3 studies	18% ± 2%	Explore
non-classical monocyte	3 studies	22% ± 5%	Explore
dendritic cell	3 studies	24% ± 4%	Explore
plasmacytoid dendritic cell	3 studies	19% ± 4%	Explore

sc-RNAseq data

Insufficient scRNA-seq data for expression of ATP13A1 at tissue level.

Tissue	GTEx Coverage	GTEx Average TPM	GTEx Number of samples	TCGA Coverage	TCGA Average TPM	TCGA Number of samples
esophagus	100%	4042.67	1445 / 1445	100%	50.79	183 / 183
ovary	100%	6328.45	180 / 180	100%	51.70	430 / 430
pancreas	100%	3597.72	328 / 328	100%	32.75	178 / 178
thymus	100%	7081.83	653 / 653	100%	40.29	605 / 605
uterus	100%	5942.88	170 / 170	100%	36.01	459 / 459
skin	100%	5001.55	1809 / 1809	100%	53.59	471 / 472
stomach	100%	4056.82	359 / 359	100%	42.63	285 / 286
intestine	100%	5384.98	966 / 966	100%	42.53	525 / 527
adrenal gland	100%	5136.62	258 / 258	100%	36.00	229 / 230
prostate	100%	6043.58	245 / 245	99%	41.34	499 / 502
breast	100%	4960.96	459 / 459	99%	40.16	1110 / 1118
kidney	100%	4525.33	89 / 89	99%	29.06	894 / 901
bladder	100%	4655.81	21 / 21	99%	39.28	499 / 504
lung	100%	4844.71	577 / 578	99%	36.04	1143 / 1155
brain	99%	3266.48	2606 / 2642	100%	38.26	705 / 705
liver	100%	2852.35	226 / 226	98%	25.35	399 / 406
adipose	100%	4265.72	1204 / 1204	0%	0	0 / 0
eye	0%	0	0 / 0	100%	64.35	80 / 80
lymph node	0%	0	0 / 0	100%	50.69	29 / 29
spleen	100%	9998.55	241 / 241	0%	0	0 / 0
tonsil	0%	0	0 / 0	100%	32.35	45 / 45
ureter	0%	0	0 / 0	100%	32.13	1 / 1
blood vessel	100%	4048.86	1334 / 1335	0%	0	0 / 0
muscle	99%	2247.62	794 / 803	0%	0	0 / 0
heart	98%	2148.04	848 / 861	0%	0	0 / 0
peripheral blood	98%	4351.55	914 / 929	0%	0	0 / 0
abdomen	0%	0	0 / 0	0%	0	0 / 0
bone marrow	0%	0	0 / 0	0%	0	0 / 0
diaphragm	0%	0	0 / 0	0%	0	0 / 0
gingiva	0%	0	0 / 0	0%	0	0 / 0
nasal cavity	0%	0	0 / 0	0%	0	0 / 0
nasopharynx	0%	0	0 / 0	0%	0	0 / 0
nose	0%	0	0 / 0	0%	0	0 / 0
placenta	0%	0	0 / 0	0%	0	0 / 0
spinal column	0%	0	0 / 0	0%	0	0 / 0

GO_0034220	Biological process	monoatomic ion transmembrane transport
GO_0015031	Biological process	protein transport
GO_0006874	Biological process	intracellular calcium ion homeostasis
GO_0071421	Biological process	manganese ion transmembrane transport
GO_0140569	Biological process	extraction of mislocalized protein from ER membrane
GO_0055085	Biological process	transmembrane transport
GO_0016020	Cellular component	membrane
GO_0005789	Cellular component	endoplasmic reticulum membrane
GO_0140567	Molecular function	membrane protein dislocase activity
GO_0015662	Molecular function	P-type ion transporter activity
GO_0015410	Molecular function	ABC-type manganese transporter activity
GO_0019829	Molecular function	ATPase-coupled monoatomic cation transmembrane transporter activity
GO_0016887	Molecular function	ATP hydrolysis activity
GO_0046872	Molecular function	metal ion binding
GO_0005524	Molecular function	ATP binding

Gene name	ATP13A1
Protein name	Endoplasmic reticulum transmembrane helix translocase (EC 7.4.2.-) (Endoplasmic reticulum P5A-ATPase) ATPase 13A1
Synonyms	ATP13A CGI-152 KIAA1825
Description	FUNCTION: Endoplasmic reticulum translocase required to remove mitochondrial transmembrane proteins mistargeted to the endoplasmic reticulum . Acts as a dislocase that mediates the ATP-dependent extraction of mislocalized mitochondrial transmembrane proteins from the endoplasmic reticulum membrane . Specifically binds mitochondrial tail-anchored transmembrane proteins: has an atypically large substrate-binding pocket that recognizes and binds moderately hydrophobic transmembranes with short hydrophilic lumenal domains . .
Accessions	ENST00000455627.1 Q9HD20 ENST00000291503.9 [Q9HD20-2] ENST00000357324.11 [Q9HD20-1] H7C3H2

ATP13A1 report