Name | Number of supported studies | Average coverage | |
---|---|---|---|
squamous epithelial cell | 4 studies | 33% ± 14% | |
ciliated cell | 3 studies | 44% ± 10% |
Insufficient scRNA-seq data for expression of ATG9B at tissue level.
Tissue | GTEx Coverage | GTEx Average TPM | GTEx Number of samples | TCGA Coverage | TCGA Average TPM | TCGA Number of samples |
---|---|---|---|---|---|---|
esophagus | 39% | 2395.31 | 557 / 1445 | 67% | 3.65 | 123 / 183 |
skin | 70% | 3172.89 | 1268 / 1809 | 34% | 0.84 | 159 / 472 |
uterus | 14% | 182.22 | 24 / 170 | 81% | 4.54 | 372 / 459 |
spleen | 93% | 611.71 | 224 / 241 | 0% | 0 | 0 / 0 |
lung | 29% | 152.18 | 166 / 578 | 64% | 2.77 | 739 / 1155 |
ovary | 1% | 28.97 | 2 / 180 | 81% | 2.85 | 348 / 430 |
pancreas | 0% | 1.27 | 1 / 328 | 80% | 3.47 | 143 / 178 |
adrenal gland | 9% | 37.23 | 22 / 258 | 71% | 5.88 | 164 / 230 |
breast | 29% | 171.57 | 131 / 459 | 49% | 1.37 | 550 / 1118 |
prostate | 24% | 90.79 | 59 / 245 | 51% | 1.09 | 256 / 502 |
tonsil | 0% | 0 | 0 / 0 | 73% | 2.24 | 33 / 45 |
brain | 49% | 282.47 | 1304 / 2642 | 24% | 0.59 | 168 / 705 |
bladder | 5% | 13.57 | 1 / 21 | 65% | 3.08 | 330 / 504 |
intestine | 3% | 13.03 | 31 / 966 | 66% | 2.31 | 348 / 527 |
stomach | 2% | 25.56 | 8 / 359 | 64% | 2.00 | 184 / 286 |
kidney | 4% | 21.34 | 4 / 89 | 35% | 1.30 | 312 / 901 |
lymph node | 0% | 0 | 0 / 0 | 24% | 0.37 | 7 / 29 |
thymus | 4% | 13.94 | 27 / 653 | 16% | 0.38 | 95 / 605 |
adipose | 15% | 83.42 | 175 / 1204 | 0% | 0 | 0 / 0 |
liver | 0% | 1.69 | 1 / 226 | 8% | 0.19 | 31 / 406 |
eye | 0% | 0 | 0 / 0 | 8% | 0.12 | 6 / 80 |
heart | 4% | 15.73 | 35 / 861 | 0% | 0 | 0 / 0 |
peripheral blood | 3% | 11.04 | 30 / 929 | 0% | 0 | 0 / 0 |
blood vessel | 2% | 8.33 | 22 / 1335 | 0% | 0 | 0 / 0 |
muscle | 0% | 2.27 | 3 / 803 | 0% | 0 | 0 / 0 |
abdomen | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
bone marrow | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
diaphragm | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
gingiva | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
nasal cavity | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
nasopharynx | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
nose | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
placenta | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
spinal column | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
ureter | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 1 |
GO_0000422 | Biological process | autophagy of mitochondrion |
GO_0017121 | Biological process | plasma membrane phospholipid scrambling |
GO_0034727 | Biological process | piecemeal microautophagy of the nucleus |
GO_0061709 | Biological process | reticulophagy |
GO_0060349 | Biological process | bone morphogenesis |
GO_0097300 | Biological process | programmed necrotic cell death |
GO_0000045 | Biological process | autophagosome assembly |
GO_0034497 | Biological process | protein localization to phagophore assembly site |
GO_0005789 | Cellular component | endoplasmic reticulum membrane |
GO_0005802 | Cellular component | trans-Golgi network |
GO_0034045 | Cellular component | phagophore assembly site membrane |
GO_0000139 | Cellular component | Golgi membrane |
GO_0055038 | Cellular component | recycling endosome membrane |
GO_0000407 | Cellular component | phagophore assembly site |
GO_0005776 | Cellular component | autophagosome |
GO_0017128 | Molecular function | phospholipid scramblase activity |
Gene name | ATG9B |
Protein name | Autophagy-related protein 9B (APG9-like 2) (Nitric oxide synthase 3-overlapping antisense gene protein) (Protein sONE) |
Synonyms | NOS3AS APG9L2 |
Description | FUNCTION: Phospholipid scramblase involved in autophagy by mediating autophagosomal membrane expansion. Cycles between the preautophagosomal structure/phagophore assembly site (PAS) and the cytoplasmic vesicle pool and supplies membrane for the growing autophagosome. Lipid scramblase activity plays a key role in preautophagosomal structure/phagophore assembly by distributing the phospholipids that arrive through ATG2 (ATG2A or ATG2B) from the cytoplasmic to the luminal leaflet of the bilayer, thereby driving autophagosomal membrane expansion (By similarity). In addition to autophagy, also plays a role in necrotic cell death (By similarity). . |
Accessions | ENST00000469530.4 [Q674R7-1] ENST00000605952.5 [Q674R7-1] ENST00000639579.2 [Q674R7-1] Q674R7 |