Name | Number of supported studies | Average coverage | |
|---|---|---|---|
| endothelial cell | 11 studies | 22% ± 6% | |
| astrocyte | 11 studies | 30% ± 15% | |
| endothelial cell of artery | 8 studies | 35% ± 13% | |
| vein endothelial cell | 8 studies | 26% ± 12% | |
| ciliated cell | 6 studies | 39% ± 26% | |
| epithelial cell | 5 studies | 39% ± 29% | |
| secretory cell | 5 studies | 39% ± 12% | |
| epithelial cell of proximal tubule | 5 studies | 22% ± 9% | |
| respiratory goblet cell | 4 studies | 39% ± 9% | |
| GABAergic neuron | 4 studies | 33% ± 10% | |
| glutamatergic neuron | 4 studies | 36% ± 13% | |
| abnormal cell | 4 studies | 22% ± 7% | |
| goblet cell | 4 studies | 26% ± 7% | |
| oligodendrocyte | 4 studies | 18% ± 3% | |
| basal cell | 3 studies | 21% ± 2% | |
| kidney loop of Henle epithelial cell | 3 studies | 26% ± 4% | |
| retinal ganglion cell | 3 studies | 40% ± 23% | |
| Mueller cell | 3 studies | 20% ± 5% | |
| endothelial cell of vascular tree | 3 studies | 25% ± 5% | |
| classical monocyte | 3 studies | 16% ± 1% | |
| interneuron | 3 studies | 33% ± 18% | |
| neuron | 3 studies | 29% ± 2% | |
| oligodendrocyte precursor cell | 3 studies | 21% ± 4% |
Name | Number of supported studies | Average coverage | |
|---|---|---|---|
| brain | 5 studies | 26% ± 7% |
Tissue | GTEx Coverage | GTEx Average TPM | GTEx Number of samples | TCGA Coverage | TCGA Average TPM | TCGA Number of samples |
|---|---|---|---|---|---|---|
| brain | 100% | 3469.90 | 2641 / 2642 | 98% | 20.91 | 693 / 705 |
| prostate | 91% | 1245.42 | 224 / 245 | 95% | 20.51 | 478 / 502 |
| kidney | 100% | 1960.71 | 89 / 89 | 79% | 23.32 | 716 / 901 |
| lung | 100% | 1636.10 | 576 / 578 | 45% | 5.73 | 515 / 1155 |
| pancreas | 67% | 439.21 | 221 / 328 | 61% | 6.16 | 109 / 178 |
| breast | 90% | 781.72 | 411 / 459 | 35% | 4.17 | 387 / 1118 |
| intestine | 63% | 434.22 | 604 / 966 | 61% | 6.84 | 322 / 527 |
| stomach | 71% | 643.93 | 256 / 359 | 52% | 4.60 | 148 / 286 |
| thymus | 67% | 340.69 | 437 / 653 | 29% | 2.05 | 177 / 605 |
| ovary | 3% | 17.83 | 6 / 180 | 93% | 32.85 | 398 / 430 |
| adipose | 92% | 875.68 | 1104 / 1204 | 0% | 0 | 0 / 0 |
| uterus | 42% | 446.31 | 72 / 170 | 44% | 14.08 | 203 / 459 |
| bladder | 29% | 128.81 | 6 / 21 | 29% | 3.31 | 146 / 504 |
| esophagus | 22% | 112.52 | 314 / 1445 | 27% | 2.54 | 49 / 183 |
| adrenal gland | 8% | 32.97 | 21 / 258 | 39% | 2.85 | 90 / 230 |
| liver | 26% | 224.27 | 59 / 226 | 20% | 2.14 | 81 / 406 |
| skin | 7% | 30.35 | 120 / 1809 | 39% | 3.94 | 185 / 472 |
| tonsil | 0% | 0 | 0 / 0 | 40% | 3.97 | 18 / 45 |
| eye | 0% | 0 | 0 / 0 | 30% | 2.07 | 24 / 80 |
| muscle | 29% | 143.43 | 234 / 803 | 0% | 0 | 0 / 0 |
| lymph node | 0% | 0 | 0 / 0 | 28% | 2.05 | 8 / 29 |
| spleen | 24% | 102.22 | 59 / 241 | 0% | 0 | 0 / 0 |
| heart | 21% | 113.05 | 178 / 861 | 0% | 0 | 0 / 0 |
| blood vessel | 11% | 57.06 | 153 / 1335 | 0% | 0 | 0 / 0 |
| peripheral blood | 8% | 35.89 | 75 / 929 | 0% | 0 | 0 / 0 |
| abdomen | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| bone marrow | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| diaphragm | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| gingiva | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| nasal cavity | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| nasopharynx | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| nose | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| placenta | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| spinal column | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| ureter | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 1 |
| GO_0033345 | Biological process | asparagine catabolic process via L-aspartate |
| GO_0006508 | Biological process | proteolysis |
| GO_0001917 | Cellular component | photoreceptor inner segment |
| GO_0005829 | Cellular component | cytosol |
| GO_0005737 | Cellular component | cytoplasm |
| GO_0005634 | Cellular component | nucleus |
| GO_0004067 | Molecular function | asparaginase activity |
| GO_0008798 | Molecular function | beta-aspartyl-peptidase activity |
| GO_0003948 | Molecular function | N4-(beta-N-acetylglucosaminyl)-L-asparaginase activity |
| Gene name | ASRGL1 |
| Protein name | Isoaspartyl peptidase/L-asparaginase (EC 3.4.19.5) (EC 3.5.1.1) (Asparaginase-like protein 1) (Beta-aspartyl-peptidase) (Isoaspartyl dipeptidase) (L-asparagine amidohydrolase) [Cleaved into: Isoaspartyl peptidase/L-asparaginase alpha chain; Isoaspartyl peptidase/L-asparaginase beta chain] Isoaspartyl peptidase/L-asparaginase (EC 3.4.19.5) (EC 3.5.1.1) (Asparaginase-like protein 1) (Beta-aspartyl-peptidase) (Isoaspartyl dipeptidase) (L-asparagine amidohydrolase) Asparaginase and isoaspartyl peptidase 1 Isoaspartyl peptidase/L-asparaginase (Asparaginase-like protein 1) (Beta-aspartyl-peptidase) (Isoaspartyl dipeptidase) (L-asparagine amidohydrolase) |
| Synonyms | ALP CRASH |
| Description | FUNCTION: Has both L-asparaginase and beta-aspartyl peptidase activity. May be involved in the production of L-aspartate, which can act as an excitatory neurotransmitter in some brain regions. Is highly active with L-Asp beta-methyl ester. Besides, has catalytic activity toward beta-aspartyl dipeptides and their methyl esters, including beta-L-Asp-L-Phe, beta-L-Asp-L-Phe methyl ester (aspartame), beta-L-Asp-L-Ala, beta-L-Asp-L-Leu and beta-L-Asp-L-Lys. Does not have aspartylglucosaminidase activity and is inactive toward GlcNAc-L-Asn. Likewise, has no activity toward glutamine. . |
| Accessions | Q7L266 ENST00000534571.5 ENST00000528206.1 ENST00000534183.5 A0A087WUG3 ENST00000526096.2 Q9BRH2 A0A087X1T8 ENST00000301776.9 [Q7L266-1] E9PJK6 A0A087WZI5 ENST00000628829.2 ENST00000415229.6 [Q7L266-1] ENST00000529226.3 |