ASMT | OmnibusX

sc-RNAseq data

Insufficient scRNA-seq data for expression of ASMT at tissue level.

Tissue	GTEx Coverage	GTEx Average TPM	GTEx Number of samples	TCGA Coverage	TCGA Average TPM	TCGA Number of samples
adrenal gland	98%	31.52	252 / 258	23%	0.90	54 / 230
uterus	99%	31.90	168 / 170	1%	0.02	4 / 459
spleen	99%	28.07	238 / 241	0%	0	0 / 0
thymus	98%	28.11	639 / 653	1%	0.01	5 / 605
prostate	98%	26.42	240 / 245	0%	0.00	1 / 502
breast	93%	20.93	429 / 459	4%	0.24	46 / 1118
ovary	94%	17.29	170 / 180	2%	0.03	7 / 430
kidney	94%	13.29	84 / 89	1%	0.02	13 / 901
blood vessel	95%	18.24	1271 / 1335	0%	0	0 / 0
lung	93%	15.60	535 / 578	2%	0.08	26 / 1155
intestine	93%	18.74	894 / 966	2%	0.03	11 / 527
stomach	89%	13.56	319 / 359	6%	0.20	16 / 286
adipose	92%	16.12	1109 / 1204	0%	0	0 / 0
bladder	90%	21.90	19 / 21	2%	0.03	8 / 504
esophagus	86%	14.95	1249 / 1445	2%	0.04	4 / 183
brain	86%	14.46	2281 / 2642	1%	0.22	7 / 705
peripheral blood	86%	22.30	801 / 929	0%	0	0 / 0
skin	82%	13.47	1483 / 1809	3%	0.04	14 / 472
pancreas	81%	10.13	266 / 328	1%	0.02	2 / 178
lymph node	0%	0	0 / 0	79%	7.06	23 / 29
liver	69%	7.51	155 / 226	1%	0.01	3 / 406
heart	69%	8.04	596 / 861	0%	0	0 / 0
muscle	47%	3.71	378 / 803	0%	0	0 / 0
eye	0%	0	0 / 0	15%	0.24	12 / 80
tonsil	0%	0	0 / 0	2%	0.37	1 / 45
abdomen	0%	0	0 / 0	0%	0	0 / 0
bone marrow	0%	0	0 / 0	0%	0	0 / 0
diaphragm	0%	0	0 / 0	0%	0	0 / 0
gingiva	0%	0	0 / 0	0%	0	0 / 0
nasal cavity	0%	0	0 / 0	0%	0	0 / 0
nasopharynx	0%	0	0 / 0	0%	0	0 / 0
nose	0%	0	0 / 0	0%	0	0 / 0
placenta	0%	0	0 / 0	0%	0	0 / 0
spinal column	0%	0	0 / 0	0%	0	0 / 0
ureter	0%	0	0 / 0	0%	0	0 / 1

GO_0006412	Biological process	translation
GO_0046219	Biological process	indolalkylamine biosynthetic process
GO_0006629	Biological process	lipid metabolic process
GO_0030187	Biological process	melatonin biosynthetic process
GO_0032259	Biological process	methylation
GO_0005829	Cellular component	cytosol
GO_0008171	Molecular function	O-methyltransferase activity
GO_0042803	Molecular function	protein homodimerization activity
GO_0008172	Molecular function	S-methyltransferase activity
GO_0017096	Molecular function	acetylserotonin O-methyltransferase activity
GO_0042802	Molecular function	identical protein binding

Gene name	ASMT
Protein name	Acetylserotonin O-methyltransferase (EC 2.1.1.4) (Hydroxyindole O-methyltransferase) Acetylserotonin O-methyltransferase Acetylserotonin O-methyltransferase (EC 2.1.1.4) (Hydroxyindole O-methyltransferase) (HIOMT)
Synonyms
Description	FUNCTION: [Isoform 1]: Catalyzes the transfer of a methyl group onto N-acetylserotonin, producing melatonin (N-acetyl-5-methoxytryptamine). .; FUNCTION: [Isoform 2]: Does not show Acetylserotonin O-methyltransferase activity. .; FUNCTION: [Isoform 3]: Does not show Acetylserotonin O-methyltransferase activity. . FUNCTION: Catalyzes the transfer of a methyl group onto N-acetylserotonin, producing melatonin (N-acetyl-5-methoxytryptamine). . FUNCTION: Catalyzes the transfer of a methyl group onto N-acetylserotonin, producing melatonin (N-acetyl-5-methoxytryptamine). . FUNCTION: Catalyzes the transfer of a methyl group onto N-acetylserotonin, producing melatonin (N-acetyl-5-methoxytryptamine). .
Accessions	P46597 ENST00000381241.9 [P46597-3] X5D311 ENST00000711209.1 [P46597-1] ENST00000711206.1 ENST00000381229.9 [P46597-1] ENST00000711210.1 [P46597-3] X5D784 I7HFW6 ENST00000432523.6 X5D2A4 ENST00000711208.1 [P46597-2] ENST00000381233.8 [P46597-2]

ASMT report