ASB4 report

I. Expression across cell types

Insufficient scRNA-seq data for expression of ASB4 at single-cell level.

II. Expression across tissues

sc-RNAseq data

Insufficient scRNA-seq data for expression of ASB4 at tissue level.

III. Associated gene sets

GO_2001214Biological processpositive regulation of vasculogenesis
GO_0051865Biological processprotein autoubiquitination
GO_0035556Biological processintracellular signal transduction
GO_0031466Cellular componentCul5-RING ubiquitin ligase complex
GO_0005829Cellular componentcytosol
GO_0031462Cellular componentCul2-RING ubiquitin ligase complex
GO_0061630Molecular functionubiquitin protein ligase activity
GO_0004842Molecular functionubiquitin-protein transferase activity
GO_0031625Molecular functionubiquitin protein ligase binding

IV. Literature review

[source]
Gene nameASB4
Protein nameAnkyrin repeat and SOCS box protein 4 (ASB-4)
Synonyms
DescriptionFUNCTION: Probable substrate-recognition component of a SCF-like ECS (Elongin-Cullin-SOCS-box protein) E3 ubiquitin-protein ligase complex which mediates the ubiquitination and subsequent proteasomal degradation of target proteins. Promotes differentiation and maturation of the vascular lineage by an oxygen-dependent mechanism (By similarity). .

AccessionsQ9Y574
ENST00000428113.5 [Q9Y574-2]
ENST00000325885.6 [Q9Y574-1]