AS3MT report

I. Expression across cell types

Insufficient scRNA-seq data for expression of AS3MT at single-cell level.

II. Expression across tissues

sc-RNAseq data

Insufficient scRNA-seq data for expression of AS3MT at tissue level.

III. Associated gene sets

GO_0009404Biological processtoxin metabolic process
GO_0018872Biological processarsonoacetate metabolic process
GO_0032259Biological processmethylation
GO_0005829Cellular componentcytosol
GO_0030791Molecular functionarsenite methyltransferase activity

IV. Literature review

[source]
Gene nameAS3MT
Protein nameArsenite methyltransferase (EC 2.1.1.137) (Methylarsonite methyltransferase) (S-adenosyl-L-methionine:arsenic(III) methyltransferase)
SynonymsCYT19
DescriptionFUNCTION: Catalyzes the transfer of a methyl group from AdoMet to trivalent arsenicals producing methylated and dimethylated arsenicals . It methylates arsenite to form methylarsonate, Me-AsO(3)H(2), which is reduced by methylarsonate reductase to methylarsonite, Me-As(OH)2 . Methylarsonite is also a substrate and it is converted into the much less toxic compound dimethylarsinate (cacodylate), Me(2)As(O)-OH . .

AccessionsQ9HBK9
ENST00000369880.8 [Q9HBK9-1]