APOBR | OmnibusX

Name	Number of supported studies	Average coverage
classical monocyte	11 studies	27% ± 11%	Explore
monocyte	4 studies	24% ± 5%	Explore
conventional dendritic cell	4 studies	25% ± 9%	Explore
macrophage	4 studies	21% ± 4%	Explore
neutrophil	3 studies	26% ± 9%	Explore
myeloid cell	3 studies	18% ± 1%	Explore
dendritic cell	3 studies	34% ± 10%	Explore

sc-RNAseq data

Insufficient scRNA-seq data for expression of APOBR at tissue level.

Tissue	GTEx Coverage	GTEx Average TPM	GTEx Number of samples	TCGA Coverage	TCGA Average TPM	TCGA Number of samples
lung	100%	2067.01	578 / 578	90%	11.68	1045 / 1155
bladder	86%	738.57	18 / 21	88%	19.85	446 / 504
prostate	78%	315.40	192 / 245	86%	5.75	432 / 502
intestine	70%	2290.85	674 / 966	93%	32.63	492 / 527
breast	66%	251.09	301 / 459	93%	16.27	1039 / 1118
stomach	64%	223.61	230 / 359	94%	23.70	270 / 286
thymus	64%	199.25	421 / 653	80%	8.85	482 / 605
skin	62%	197.74	1113 / 1809	74%	7.71	351 / 472
liver	72%	219.73	162 / 226	58%	4.10	236 / 406
kidney	35%	129.43	31 / 89	88%	9.81	791 / 901
esophagus	47%	136.75	673 / 1445	75%	5.92	138 / 183
uterus	35%	90.71	59 / 170	85%	10.15	388 / 459
pancreas	22%	84.47	73 / 328	94%	15.53	168 / 178
adrenal gland	85%	317.42	220 / 258	29%	1.61	67 / 230
lymph node	0%	0	0 / 0	100%	16.84	29 / 29
spleen	100%	6216.07	241 / 241	0%	0	0 / 0
ureter	0%	0	0 / 0	100%	3.79	1 / 1
peripheral blood	99%	14217.65	923 / 929	0%	0	0 / 0
tonsil	0%	0	0 / 0	98%	15.08	44 / 45
brain	20%	67.48	541 / 2642	74%	6.61	525 / 705
adipose	79%	407.22	949 / 1204	0%	0	0 / 0
ovary	13%	32.45	23 / 180	56%	3.56	241 / 430
blood vessel	35%	154.63	467 / 1335	0%	0	0 / 0
eye	0%	0	0 / 0	33%	2.20	26 / 80
heart	27%	78.77	233 / 861	0%	0	0 / 0
muscle	1%	2.74	11 / 803	0%	0	0 / 0
abdomen	0%	0	0 / 0	0%	0	0 / 0
bone marrow	0%	0	0 / 0	0%	0	0 / 0
diaphragm	0%	0	0 / 0	0%	0	0 / 0
gingiva	0%	0	0 / 0	0%	0	0 / 0
nasal cavity	0%	0	0 / 0	0%	0	0 / 0
nasopharynx	0%	0	0 / 0	0%	0	0 / 0
nose	0%	0	0 / 0	0%	0	0 / 0
placenta	0%	0	0 / 0	0%	0	0 / 0
spinal column	0%	0	0 / 0	0%	0	0 / 0

GO_0008203	Biological process	cholesterol metabolic process
GO_0016192	Biological process	vesicle-mediated transport
GO_0006641	Biological process	triglyceride metabolic process
GO_0006869	Biological process	lipid transport
GO_0042627	Cellular component	chylomicron
GO_0034362	Cellular component	low-density lipoprotein particle
GO_0005886	Cellular component	plasma membrane
GO_0034361	Cellular component	very-low-density lipoprotein particle
GO_0016020	Cellular component	membrane
GO_0030229	Molecular function	very-low-density lipoprotein particle receptor activity

Gene name	APOBR
Protein name	Apolipoprotein B receptor (Apolipoprotein B-100 receptor) (Apolipoprotein B-48 receptor) (Apolipoprotein B48 receptor) (apoB-48R)
Synonyms	APOB48R
Description	FUNCTION: Macrophage receptor that binds to the apolipoprotein B48 (APOB) of dietary triglyceride (TG)-rich lipoproteins (TRL) or to a like domain of APOB in hypertriglyceridemic very low density lipoprotein (HTG-VLDL). Binds and internalizes TRL when out of the context of the macrophage. May provide essential lipids to reticuloendothelial cells. Could also be involved in foam cell formation with elevated TRL and remnant lipoprotein (RLP). Mediates the rapid high-affinity uptake of chylomicrons (CM), HTG-VLDL, and trypsinized (tryp) VLDL devoid of APOE in vitro in macrophages. .
Accessions	ENST00000564831.6 [Q0VD83-4] Q0VD83

APOBR report