ANO5 report

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I. Expression across cell types

Cell ontologyData table

Name	Number of supported studies	Average coverage
glutamatergic neuron	9 studies	52% ± 27%	Explore
astrocyte	8 studies	39% ± 21%	Explore
oligodendrocyte precursor cell	8 studies	31% ± 13%	Explore
GABAergic neuron	7 studies	53% ± 27%	Explore
cardiac muscle cell	5 studies	42% ± 11%	Explore
interneuron	4 studies	61% ± 29%	Explore
neuron	3 studies	26% ± 2%	Explore
endothelial cell	3 studies	28% ± 10%	Explore
GABAergic interneuron	3 studies	29% ± 10%	Explore
retinal ganglion cell	3 studies	28% ± 10%	Explore

II. Expression across tissues

sc-RNAseq dataData table

Name	Number of supported studies	Average coverage
brain	10 studies	36% ± 25%	Explore
heart	3 studies	20% ± 3%	Explore

Bulk RNAseq dataData table

Tissue	GTEx Coverage	GTEx Average TPM	GTEx Number of samples	TCGA Coverage	TCGA Average TPM	TCGA Number of samples
adrenal gland	100%	1000.74	258 / 258	90%	11.67	207 / 230
pancreas	99%	600.95	325 / 328	79%	2.65	140 / 178
brain	85%	909.91	2246 / 2642	87%	6.19	611 / 705
prostate	95%	772.65	233 / 245	75%	2.81	377 / 502
thymus	95%	487.74	620 / 653	72%	2.15	436 / 605
liver	87%	359.23	196 / 226	63%	1.97	256 / 406
kidney	90%	350.03	80 / 89	57%	3.31	513 / 901
stomach	97%	780.99	350 / 359	40%	1.57	113 / 286
intestine	98%	766.33	942 / 966	31%	0.99	164 / 527
esophagus	63%	776.28	913 / 1445	50%	2.35	91 / 183
lung	66%	228.22	380 / 578	43%	1.48	499 / 1155
uterus	79%	311.54	135 / 170	26%	1.23	120 / 459
muscle	100%	6498.34	803 / 803	0%	0	0 / 0
heart	96%	3107.72	823 / 861	0%	0	0 / 0
bladder	71%	670.62	15 / 21	23%	0.64	114 / 504
blood vessel	89%	558.41	1192 / 1335	0%	0	0 / 0
eye	0%	0	0 / 0	64%	2.60	51 / 80
ovary	41%	119.11	73 / 180	19%	0.44	83 / 430
spleen	54%	185.15	131 / 241	0%	0	0 / 0
breast	15%	48.12	68 / 459	36%	1.89	397 / 1118
skin	0%	2.14	7 / 1809	40%	1.59	188 / 472
adipose	20%	59.10	240 / 1204	0%	0	0 / 0
peripheral blood	12%	86.93	110 / 929	0%	0	0 / 0
lymph node	0%	0	0 / 0	10%	0.28	3 / 29
tonsil	0%	0	0 / 0	7%	0.21	3 / 45
abdomen	0%	0	0 / 0	0%	0	0 / 0
bone marrow	0%	0	0 / 0	0%	0	0 / 0
diaphragm	0%	0	0 / 0	0%	0	0 / 0
gingiva	0%	0	0 / 0	0%	0	0 / 0
nasal cavity	0%	0	0 / 0	0%	0	0 / 0
nasopharynx	0%	0	0 / 0	0%	0	0 / 0
nose	0%	0	0 / 0	0%	0	0 / 0
placenta	0%	0	0 / 0	0%	0	0 / 0
spinal column	0%	0	0 / 0	0%	0	0 / 0
ureter	0%	0	0 / 0	0%	0	0 / 1