ANO3 | OmnibusX

Name	Number of supported studies	Average coverage
glutamatergic neuron	11 studies	43% ± 24%	Explore

Name	Number of supported studies	Average coverage
brain	5 studies	39% ± 21%	Explore

Tissue	GTEx Coverage	GTEx Average TPM	GTEx Number of samples	TCGA Coverage	TCGA Average TPM	TCGA Number of samples
brain	73%	4473.10	1934 / 2642	46%	2.04	327 / 705
kidney	70%	143.57	62 / 89	41%	1.32	371 / 901
adipose	90%	330.06	1078 / 1204	0%	0	0 / 0
breast	61%	157.50	282 / 459	16%	0.75	184 / 1118
adrenal gland	52%	78.28	134 / 258	14%	0.39	32 / 230
blood vessel	50%	102.63	667 / 1335	0%	0	0 / 0
skin	31%	202.93	569 / 1809	18%	1.18	86 / 472
lung	36%	56.63	206 / 578	13%	0.51	151 / 1155
thymus	32%	44.08	207 / 653	12%	0.21	74 / 605
liver	33%	49.55	75 / 226	10%	0.44	40 / 406
uterus	29%	44.74	49 / 170	6%	0.29	28 / 459
pancreas	20%	34.10	66 / 328	8%	0.23	15 / 178
intestine	21%	31.04	204 / 966	4%	0.11	19 / 527
heart	16%	33.30	137 / 861	0%	0	0 / 0
esophagus	0%	0.60	6 / 1445	12%	0.37	22 / 183
ovary	7%	13.64	13 / 180	3%	0.12	13 / 430
stomach	1%	0.55	2 / 359	7%	0.13	19 / 286
bladder	0%	0	0 / 21	7%	0.18	36 / 504
lymph node	0%	0	0 / 0	7%	0.52	2 / 29
prostate	2%	2.41	4 / 245	4%	0.15	21 / 502
peripheral blood	3%	4.29	28 / 929	0%	0	0 / 0
spleen	2%	2.23	4 / 241	0%	0	0 / 0
muscle	0%	0.75	2 / 803	0%	0	0 / 0
abdomen	0%	0	0 / 0	0%	0	0 / 0
bone marrow	0%	0	0 / 0	0%	0	0 / 0
diaphragm	0%	0	0 / 0	0%	0	0 / 0
eye	0%	0	0 / 0	0%	0	0 / 80
gingiva	0%	0	0 / 0	0%	0	0 / 0
nasal cavity	0%	0	0 / 0	0%	0	0 / 0
nasopharynx	0%	0	0 / 0	0%	0	0 / 0
nose	0%	0	0 / 0	0%	0	0 / 0
placenta	0%	0	0 / 0	0%	0	0 / 0
spinal column	0%	0	0 / 0	0%	0	0 / 0
tonsil	0%	0	0 / 0	0%	0	0 / 45
ureter	0%	0	0 / 0	0%	0	0 / 1

GO_0061590	Biological process	calcium activated phosphatidylcholine scrambling
GO_0034220	Biological process	monoatomic ion transmembrane transport
GO_0050982	Biological process	detection of mechanical stimulus
GO_0016048	Biological process	detection of temperature stimulus
GO_0061591	Biological process	calcium activated galactosylceramide scrambling
GO_1902476	Biological process	chloride transmembrane transport
GO_0051649	Biological process	establishment of localization in cell
GO_0005886	Cellular component	plasma membrane
GO_0046983	Molecular function	protein dimerization activity
GO_0005229	Molecular function	intracellularly calcium-gated chloride channel activity
GO_0005254	Molecular function	chloride channel activity
GO_0017128	Molecular function	phospholipid scramblase activity

Gene name	ANO3
Protein name	Anoctamin 3 Anoctamin Anoctamin-3 (Transmembrane protein 16C)
Synonyms	TMEM16C GENX-3947 C11orf25
Description	FUNCTION: Has calcium-dependent phospholipid scramblase activity; scrambles phosphatidylcholine and galactosylceramide (By similarity). Seems to act as potassium channel regulator and may inhibit pain signaling; can facilitate KCNT1/Slack channel activity by promoting its full single-channel conductance at very low sodium concentrations and by increasing its sodium sensitivity (By similarity). Does not exhibit calcium-activated chloride channel (CaCC) activity . .
Accessions	ENST00000256737.8 [Q9BYT9-1] ENST00000531646.1 Q9BYT9 A0A5F9ZHL6 ENST00000531568.1 [Q9BYT9-2] ENST00000672621.1 E9PQ79 ENST00000525139.5 E9PKW2

ANO3 report