I. Expression across cell types
Name | Number of supported studies  | Average coverage | |
|---|---|---|---|
| glutamatergic neuron | 4 studies | 38% ± 17% | |
| GABAergic neuron | 3 studies | 42% ± 12% | |
| astrocyte | 3 studies | 22% ± 5% |
Name | Number of supported studies | Average coverage | |
|---|---|---|---|
| glutamatergic neuron | 4 studies | 38% ± 17% | |
| GABAergic neuron | 3 studies | 42% ± 12% | |
| astrocyte | 3 studies | 22% ± 5% |
Name | Number of supported studies | Average coverage | |
|---|---|---|---|
| brain | 4 studies | 32% ± 10% |
Tissue | GTEx Coverage | GTEx Average TPM | GTEx Number of samples | TCGA Coverage | TCGA Average TPM | TCGA Number of samples |
|---|---|---|---|---|---|---|
| esophagus | 100% | 324.83 | 1445 / 1445 | 100% | 7.77 | 183 / 183 |
| ovary | 100% | 601.75 | 180 / 180 | 100% | 13.29 | 430 / 430 |
| stomach | 100% | 466.27 | 359 / 359 | 100% | 8.54 | 286 / 286 |
| breast | 100% | 444.67 | 459 / 459 | 100% | 10.86 | 1117 / 1118 |
| prostate | 100% | 427.94 | 245 / 245 | 100% | 9.49 | 501 / 502 |
| brain | 100% | 386.13 | 2634 / 2642 | 100% | 9.68 | 705 / 705 |
| thymus | 100% | 385.52 | 653 / 653 | 100% | 7.88 | 603 / 605 |
| uterus | 100% | 601.99 | 170 / 170 | 100% | 7.74 | 457 / 459 |
| intestine | 100% | 351.43 | 966 / 966 | 99% | 8.78 | 523 / 527 |
| bladder | 100% | 435.52 | 21 / 21 | 99% | 9.38 | 500 / 504 |
| lung | 100% | 300.70 | 576 / 578 | 99% | 7.30 | 1147 / 1155 |
| skin | 100% | 525.44 | 1809 / 1809 | 99% | 7.27 | 467 / 472 |
| pancreas | 99% | 229.61 | 326 / 328 | 99% | 6.08 | 177 / 178 |
| liver | 100% | 199.30 | 225 / 226 | 98% | 6.62 | 399 / 406 |
| kidney | 100% | 296.52 | 89 / 89 | 97% | 6.07 | 870 / 901 |
| adrenal gland | 100% | 356.53 | 258 / 258 | 97% | 7.01 | 222 / 230 |
| adipose | 100% | 364.33 | 1204 / 1204 | 0% | 0 | 0 / 0 |
| eye | 0% | 0 | 0 / 0 | 100% | 9.87 | 80 / 80 |
| lymph node | 0% | 0 | 0 / 0 | 100% | 8.16 | 29 / 29 |
| spleen | 100% | 302.52 | 241 / 241 | 0% | 0 | 0 / 0 |
| tonsil | 0% | 0 | 0 / 0 | 100% | 6.12 | 45 / 45 |
| ureter | 0% | 0 | 0 / 0 | 100% | 10.27 | 1 / 1 |
| blood vessel | 100% | 331.62 | 1334 / 1335 | 0% | 0 | 0 / 0 |
| muscle | 99% | 217.10 | 797 / 803 | 0% | 0 | 0 / 0 |
| heart | 96% | 201.12 | 828 / 861 | 0% | 0 | 0 / 0 |
| peripheral blood | 52% | 125.13 | 481 / 929 | 0% | 0 | 0 / 0 |
| abdomen | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| bone marrow | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| diaphragm | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| gingiva | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| nasal cavity | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| nasopharynx | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| nose | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| placenta | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| spinal column | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| GO_0006400 | Biological process | tRNA modification |
| GO_0005737 | Cellular component | cytoplasm |
| GO_0005634 | Cellular component | nucleus |
| Gene name | ANKRD16 |
| Protein name | Ankyrin repeat domain-containing protein 16 |
| Synonyms | |
| Description | FUNCTION: Required to prevent the misactivation of serine (Ser) with tRNA(Ala) by promoting the hydrolysis of Ser-mischarged tRNA(Ala), thereby playing a role in translational fidelity. Binds directly to the catalytic domain of AARS/AlaRS and captures Ser that is misactivated by AARS/AlaRS, preventing the charging of Ser adenylates to tRNA(Ala) and precluding Ser misincorporation in nascent peptides. . |
| Accessions | ENST00000191063.8 [Q6P6B7-2] Q6P6B7 ENST00000380094.10 [Q6P6B7-1] ENST00000380092.8 [Q6P6B7-1] |
