Name | Number of supported studies | Average coverage | |
|---|---|---|---|
| epithelial cell | 3 studies | 29% ± 10% |
Insufficient scRNA-seq data for expression of AMT at tissue level.
Tissue | GTEx Coverage | GTEx Average TPM | GTEx Number of samples | TCGA Coverage | TCGA Average TPM | TCGA Number of samples |
|---|---|---|---|---|---|---|
| lung | 100% | 2287.09 | 578 / 578 | 1% | 0.01 | 12 / 1155 |
| bladder | 100% | 2653.24 | 21 / 21 | 1% | 0.01 | 3 / 504 |
| pancreas | 100% | 1834.18 | 328 / 328 | 1% | 0.01 | 1 / 178 |
| kidney | 100% | 2866.69 | 89 / 89 | 0% | 0.01 | 4 / 901 |
| stomach | 100% | 2035.67 | 359 / 359 | 0% | 0.00 | 1 / 286 |
| breast | 99% | 2474.37 | 456 / 459 | 1% | 0.02 | 10 / 1118 |
| ovary | 100% | 4572.39 | 180 / 180 | 0% | 0.00 | 1 / 430 |
| uterus | 100% | 3958.49 | 170 / 170 | 0% | 0.00 | 1 / 459 |
| prostate | 100% | 3911.77 | 245 / 245 | 0% | 0.00 | 1 / 502 |
| intestine | 100% | 3064.43 | 966 / 966 | 0% | 0 | 0 / 527 |
| liver | 100% | 3464.17 | 226 / 226 | 0% | 0 | 0 / 406 |
| spleen | 100% | 3043.27 | 241 / 241 | 0% | 0 | 0 / 0 |
| thymus | 100% | 3330.12 | 653 / 653 | 0% | 0 | 0 / 605 |
| blood vessel | 99% | 2316.74 | 1323 / 1335 | 0% | 0 | 0 / 0 |
| adrenal gland | 99% | 2162.45 | 255 / 258 | 0% | 0 | 0 / 230 |
| adipose | 98% | 1817.68 | 1185 / 1204 | 0% | 0 | 0 / 0 |
| esophagus | 98% | 1994.41 | 1417 / 1445 | 0% | 0 | 0 / 183 |
| heart | 98% | 1935.29 | 841 / 861 | 0% | 0 | 0 / 0 |
| brain | 96% | 1795.02 | 2541 / 2642 | 0% | 0.00 | 2 / 705 |
| skin | 90% | 1461.52 | 1630 / 1809 | 0% | 0 | 0 / 472 |
| muscle | 86% | 928.99 | 687 / 803 | 0% | 0 | 0 / 0 |
| peripheral blood | 62% | 489.97 | 577 / 929 | 0% | 0 | 0 / 0 |
| abdomen | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| bone marrow | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| diaphragm | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| eye | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 80 |
| gingiva | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| lymph node | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 29 |
| nasal cavity | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| nasopharynx | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| nose | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| placenta | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| spinal column | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| tonsil | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 45 |
| ureter | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 1 |
| GO_0006546 | Biological process | glycine catabolic process |
| GO_0019464 | Biological process | glycine decarboxylation via glycine cleavage system |
| GO_0005654 | Cellular component | nucleoplasm |
| GO_0005759 | Cellular component | mitochondrial matrix |
| GO_0005739 | Cellular component | mitochondrion |
| GO_0004047 | Molecular function | aminomethyltransferase activity |
| GO_0008483 | Molecular function | transaminase activity |
| Gene name | AMT |
| Protein name | Aminomethyltransferase, mitochondrial (EC 2.1.2.10) (Glycine cleavage system T protein) (GCVT) Aminomethyltransferase Aminomethyltransferase (EC 2.1.2.10) (Glycine cleavage system T protein) Aminomethyltransferase, mitochondrial |
| Synonyms | GCST hCG_2001997 |
| Description | FUNCTION: The glycine cleavage system catalyzes the degradation of glycine. . FUNCTION: The glycine cleavage system catalyzes the degradation of glycine. . FUNCTION: The glycine cleavage system catalyzes the degradation of glycine. . FUNCTION: The glycine cleavage system catalyzes the degradation of glycine. . FUNCTION: The glycine cleavage system catalyzes the degradation of glycine. . FUNCTION: The glycine cleavage system catalyzes the degradation of glycine. . FUNCTION: The glycine cleavage system catalyzes the degradation of glycine. . |
| Accessions | Q49A62 ENST00000637821.1 ENST00000636199.1 ENST00000430521.2 A0A1B0GV07 ENST00000636597.1 A0A1B0GTB6 A0A1B0GTV8 ENST00000273588.9 [P48728-1] A0A1B0GVD0 ENST00000635808.1 H0Y695 A0A1B0GWC4 ENST00000636522.1 [P48728-2] A0A1B0GU55 ENST00000538581.6 ENST00000636070.1 A0A1B0GTM2 ENST00000637455.1 ENST00000395338.7 [P48728-4] ENST00000638063.1 A0A1B0GUK9 ENST00000637682.1 P48728 ENST00000636865.1 ENST00000427987.6 ENST00000637059.1 C9JXJ4 ENST00000458307.6 [P48728-3] A0A1B0GTA8 A0A1B0GUU7 ENST00000462048.2 F8WF62 ENST00000399379.7 ENST00000636188.1 A0A1B0GVP5 B3KTU4 ENST00000636023.1 |