ALG11 report

I. Expression across cell types

II. Expression across tissues

III. Associated gene sets

GO_0006490Biological processoligosaccharide-lipid intermediate biosynthetic process
GO_0006487Biological processprotein N-linked glycosylation
GO_0006488Biological processdolichol-linked oligosaccharide biosynthetic process
GO_0016020Cellular componentmembrane
GO_0005789Cellular componentendoplasmic reticulum membrane
GO_0004377Molecular functionGDP-Man:Man3GlcNAc2-PP-Dol alpha-1,2-mannosyltransferase activity
GO_0000026Molecular functionalpha-1,2-mannosyltransferase activity

IV. Literature review

[source]
Gene nameALG11
Protein nameGDP-Man:Man(3)GlcNAc(2)-PP-Dol alpha-1,2-mannosyltransferase (EC 2.4.1.131) (Asparagine-linked glycosylation protein 11 homolog) (Glycolipid 2-alpha-mannosyltransferase)
GDP-Man:Man(3)GlcNAc(2)-PP-Dol alpha-1,2-mannosyltransferase (EC 2.4.1.131)
ALG11 alpha-1,2-mannosyltransferase
SynonymsGT8
DescriptionFUNCTION: Mannosyltransferase involved in the last steps of the synthesis of Man5GlcNAc(2)-PP-dolichol core oligosaccharide on the cytoplasmic face of the endoplasmic reticulum. Catalyzes the addition of the 4th and 5th mannose residues to the dolichol-linked oligosaccharide chain. .

FUNCTION: Required for N-linked oligosaccharide assembly. .

FUNCTION: Required for N-linked oligosaccharide assembly. .

AccessionsA0A3B3IS90
ENST00000679544.1
A0A7P0T8Y4
ENST00000616513.1
A0A7P0T8B1
A0A7P0T9G5
ENST00000681047.1
ENST00000523764.1
ENST00000521508.2
A0A3B3ISP7
A0A7P0Z4B5
Q2TAA5
ENST00000650049.2
ENST00000681145.1
ENST00000679359.1
ENST00000681053.1
A0A3B3ISU2
ENST00000649708.2
ENST00000649340.2
Q5TAP0
A0A087WYL8