I. Expression across cell types
Name | Number of supported studies  | Average coverage | |
|---|---|---|---|
| hepatocyte | 5 studies | 36% ± 12% | |
| epithelial cell of proximal tubule | 3 studies | 18% ± 2% | |
| GABAergic neuron | 3 studies | 24% ± 6% | |
| glutamatergic neuron | 3 studies | 31% ± 6% |
Name | Number of supported studies | Average coverage | |
|---|---|---|---|
| hepatocyte | 5 studies | 36% ± 12% | |
| epithelial cell of proximal tubule | 3 studies | 18% ± 2% | |
| GABAergic neuron | 3 studies | 24% ± 6% | |
| glutamatergic neuron | 3 studies | 31% ± 6% |
Name | Number of supported studies | Average coverage | |
|---|---|---|---|
| brain | 4 studies | 21% ± 5% |
Tissue | GTEx Coverage | GTEx Average TPM | GTEx Number of samples | TCGA Coverage | TCGA Average TPM | TCGA Number of samples |
|---|---|---|---|---|---|---|
| liver | 100% | 9354.16 | 226 / 226 | 92% | 66.47 | 375 / 406 |
| kidney | 100% | 2499.67 | 89 / 89 | 82% | 52.17 | 741 / 901 |
| brain | 99% | 348.08 | 2605 / 2642 | 25% | 0.78 | 178 / 705 |
| breast | 85% | 89.66 | 389 / 459 | 12% | 0.45 | 134 / 1118 |
| uterus | 89% | 118.37 | 151 / 170 | 8% | 6.76 | 36 / 459 |
| prostate | 95% | 172.01 | 233 / 245 | 1% | 0.05 | 4 / 502 |
| spleen | 96% | 123.10 | 231 / 241 | 0% | 0 | 0 / 0 |
| intestine | 93% | 204.55 | 898 / 966 | 3% | 0.30 | 15 / 527 |
| adrenal gland | 88% | 108.33 | 226 / 258 | 6% | 0.19 | 14 / 230 |
| blood vessel | 92% | 112.05 | 1231 / 1335 | 0% | 0 | 0 / 0 |
| lung | 83% | 78.53 | 482 / 578 | 7% | 1.36 | 85 / 1155 |
| bladder | 86% | 178.76 | 18 / 21 | 4% | 0.52 | 19 / 504 |
| esophagus | 84% | 235.98 | 1220 / 1445 | 3% | 0.36 | 5 / 183 |
| adipose | 78% | 84.88 | 934 / 1204 | 0% | 0 | 0 / 0 |
| stomach | 69% | 88.67 | 248 / 359 | 1% | 0.09 | 4 / 286 |
| thymus | 67% | 53.14 | 436 / 653 | 3% | 0.08 | 17 / 605 |
| muscle | 65% | 54.82 | 525 / 803 | 0% | 0 | 0 / 0 |
| skin | 60% | 49.25 | 1077 / 1809 | 3% | 0.09 | 13 / 472 |
| ovary | 51% | 38.68 | 92 / 180 | 2% | 0.06 | 8 / 430 |
| pancreas | 45% | 28.10 | 148 / 328 | 1% | 0.04 | 2 / 178 |
| peripheral blood | 45% | 34.47 | 417 / 929 | 0% | 0 | 0 / 0 |
| heart | 36% | 24.42 | 311 / 861 | 0% | 0 | 0 / 0 |
| tonsil | 0% | 0 | 0 / 0 | 2% | 0.06 | 1 / 45 |
| abdomen | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| bone marrow | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| diaphragm | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| eye | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 80 |
| gingiva | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| lymph node | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 29 |
| nasal cavity | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| nasopharynx | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| nose | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| placenta | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| spinal column | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| ureter | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 1 |
| GO_0097053 | Biological process | L-kynurenine catabolic process |
| GO_0042574 | Biological process | retinal metabolic process |
| GO_0042573 | Biological process | retinoic acid metabolic process |
| GO_0042904 | Biological process | 9-cis-retinoic acid biosynthetic process |
| GO_0070062 | Cellular component | extracellular exosome |
| GO_0005829 | Cellular component | cytosol |
| GO_0001758 | Molecular function | retinal dehydrogenase activity |
| GO_0047102 | Molecular function | aminomuconate-semialdehyde dehydrogenase activity |
| Gene name | ALDH8A1 |
| Protein name | Aldehyde dehydrogenase 8 family member A1 2-aminomuconic semialdehyde dehydrogenase (EC 1.2.1.32) (Aldehyde dehydrogenase 12) (Aldehyde dehydrogenase family 8 member A1) |
| Synonyms | ALDH12 |
| Description | FUNCTION: Catalyzes the NAD-dependent oxidation of 2-aminomuconic semialdehyde of the kynurenine metabolic pathway in L-tryptophan degradation. . |
| Accessions | ENST00000367847.2 [Q9H2A2-4] E9PKV1 ENST00000367845.6 [Q9H2A2-2] ENST00000349305.8 [Q9H2A2-3] ENST00000534012.1 ENST00000460753.1 ENST00000265605.7 [Q9H2A2-1] H0YF40 Q9H2A2 |
