AKR7L report

I. Expression across cell types

Insufficient scRNA-seq data for expression of AKR7L at single-cell level.

II. Expression across tissues

sc-RNAseq data

Insufficient scRNA-seq data for expression of AKR7L at tissue level.

III. Associated gene sets

GO_0005829Cellular componentcytosol
GO_0070062Cellular componentextracellular exosome
GO_0005737Cellular componentcytoplasm
GO_0004033Molecular functionaldo-keto reductase (NADPH) activity

IV. Literature review

[source]
Gene nameAKR7L
Protein nameAflatoxin B1 aldehyde reductase member 4 (EC 1.-.-.-) (AFB1 aldehyde reductase 3) (AFB1-AR 3) (Aldoketoreductase 7-like)
SynonymsAKR7A4
AFAR3
DescriptionFUNCTION: Can reduce the dialdehyde protein-binding form of aflatoxin B1 (AFB1) to the non-binding AFB1 dialcohol. May be involved in protection of liver against the toxic and carcinogenic effects of AFB1, a potent hepatocarcinogen (By similarity). .

AccessionsQ8NHP1