Insufficient scRNA-seq data for expression of AKR1E2 at single-cell level.
Insufficient scRNA-seq data for expression of AKR1E2 at tissue level.
Tissue | GTEx Coverage | GTEx Average TPM | GTEx Number of samples | TCGA Coverage | TCGA Average TPM | TCGA Number of samples |
---|---|---|---|---|---|---|
uterus | 100% | 170.22 | 170 / 170 | 85% | 6.15 | 391 / 459 |
lung | 99% | 158.67 | 575 / 578 | 83% | 4.92 | 956 / 1155 |
bladder | 100% | 201.52 | 21 / 21 | 79% | 5.02 | 399 / 504 |
intestine | 99% | 135.28 | 960 / 966 | 78% | 3.55 | 412 / 527 |
skin | 99% | 147.23 | 1796 / 1809 | 75% | 3.87 | 356 / 472 |
esophagus | 99% | 158.04 | 1430 / 1445 | 75% | 4.20 | 137 / 183 |
breast | 100% | 243.72 | 459 / 459 | 70% | 3.69 | 779 / 1118 |
adrenal gland | 96% | 90.08 | 248 / 258 | 73% | 2.77 | 169 / 230 |
pancreas | 84% | 54.52 | 276 / 328 | 85% | 3.79 | 152 / 178 |
stomach | 97% | 125.97 | 350 / 359 | 69% | 3.09 | 198 / 286 |
kidney | 98% | 102.97 | 87 / 89 | 65% | 1.72 | 586 / 901 |
ovary | 97% | 96.44 | 174 / 180 | 64% | 2.87 | 277 / 430 |
prostate | 99% | 136.71 | 242 / 245 | 58% | 1.46 | 290 / 502 |
thymus | 100% | 232.72 | 653 / 653 | 48% | 1.18 | 293 / 605 |
brain | 90% | 62.22 | 2365 / 2642 | 12% | 0.27 | 82 / 705 |
adipose | 100% | 219.95 | 1204 / 1204 | 0% | 0 | 0 / 0 |
ureter | 0% | 0 | 0 / 0 | 100% | 12.96 | 1 / 1 |
blood vessel | 100% | 222.15 | 1334 / 1335 | 0% | 0 | 0 / 0 |
spleen | 98% | 91.12 | 237 / 241 | 0% | 0 | 0 / 0 |
heart | 98% | 117.68 | 844 / 861 | 0% | 0 | 0 / 0 |
tonsil | 0% | 0 | 0 / 0 | 93% | 4.99 | 42 / 45 |
muscle | 76% | 44.61 | 610 / 803 | 0% | 0 | 0 / 0 |
eye | 0% | 0 | 0 / 0 | 64% | 1.39 | 51 / 80 |
liver | 44% | 21.47 | 99 / 226 | 18% | 0.69 | 75 / 406 |
peripheral blood | 19% | 9.45 | 172 / 929 | 0% | 0 | 0 / 0 |
lymph node | 0% | 0 | 0 / 0 | 10% | 0.13 | 3 / 29 |
abdomen | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
bone marrow | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
diaphragm | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
gingiva | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
nasal cavity | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
nasopharynx | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
nose | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
placenta | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
spinal column | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
GO_0005829 | Cellular component | cytosol |
GO_0016491 | Molecular function | oxidoreductase activity |
GO_0004032 | Molecular function | aldose reductase (NADPH) activity |
GO_0050571 | Molecular function | 1,5-anhydro-D-fructose reductase activity |
Gene name | AKR1E2 |
Protein name | 1,5-anhydro-D-fructose reductase (EC 1.1.1.263) (Aldo-keto reductase family 1 member C-like protein 2) (Aldo-keto reductase family 1 member E2) 1,5-anhydro-D-fructose reductase (AF reductase) (EC 1.1.1.263) (Aldo-keto reductase family 1 member C-like protein 2) (Aldo-keto reductase family 1 member E2) (LoopADR) (Testis aldo-keto reductase) (htAKR) (Testis-specific protein) (hTSP) Aldo-keto reductase family 1 member E2 Aldo-keto reductase family 1 member E2 (Aldo-keto reductase family 1, member C-like 2, isoform CRA_c) |
Synonyms | AKR1CL2 hCG_22604 AKRDC1 |
Description | FUNCTION: Catalyzes the NADPH-dependent reduction of 1,5-anhydro-D-fructose (AF) to 1,5-anhydro-D-glucitol (By similarity). Has low NADPH-dependent reductase activity towards 9,10-phenanthrenequinone (in vitro) . . |
Accessions | ENST00000298375.12 [Q96JD6-1] ENST00000533295.5 ENST00000463345.5 [Q96JD6-4] ENST00000487985.1 ENST00000532248.5 [Q96JD6-3] ENST00000345253.9 [Q96JD6-5] E9PK93 G3V1C1 ENST00000525572.1 ENST00000334019.4 [Q96JD6-2] H0YCI2 Q96JD6 ENST00000474119.5 H0YDE8 |